目的:机械通气损伤机制复杂,是由多种炎症因子和炎症通路参与的炎症反应。
Objective:The mechanism of ventilator-induced lung injury(VILI) is complicated, Which is inflammation participated by many inflammatory factors and pathways.
来自Dana - Farber癌症研究所的资深作者Charles Fuchs医学博士补充说,“了解影响结直肠癌的风险的具体的炎症通路将是至关重要的。
Charles Fuchs, MD, MPH, of Dana-Farber, the study's senior author adds, "Understanding the specific inflammatory pathways that influence risk for colorectal cancer will be critical."
在任一点阻断这条通路,或者沉默与炎症小体形成相关的基因或者编码半胱天冬酶- 1的基因,都能导致细胞死亡数目增加。
Interrupting the pathway at any point, either by silencing the genes responsible for the inflammasome formation or the gene for caspase-1, resulted in increased cell death.
斑秃发病机制的研究,重点是早期病程中炎症和毛囊周期信号传导通路的改变机制。
Research on pathogenesis of alopecia areata, with a focus on inflammation in the early stage of the disease and dynamics of signal transduction pathway of hair cycle.
泛素- 蛋白酶体通路介导细胞蛋白质的降解,在细胞周期、基因转录及表达、 抗原提呈和炎症演进等方面发挥调控作用。
Ubiquitin-proteasome pathway mediates the degradation of cell protein and modulates cell cycle, gene translation and expression, antigen presentation and inflammation development.
涉及的功能通路包括炎症反应、氧化应激、视黄醇代谢、脂肪酸代谢、激肽和过敏毒素的调节等。
The function of these proteins involved in inflammatory responses, oxidative stress, retinol metabolism, fatty acid metabolism and regulation of kinins and anaphylatoxins.
炎症时释放的许多炎症介质都能够与TRPV 1发生相互作用,产生疼痛或痛觉过敏,并且通过各种不同的信号通路来调制TRPV1的活性。
In inflammatory pain, a number of inflammatory mediators are released, which modulate TRPV1 activity through various signal pathways or interact with TRPV1 generating pain or hyperalgesia.
研究人员已经提出对自体免疫与炎症性疾病中TLR介导的通路进行深入研究。
The involvement of TLR-mediated pathways in autoimmune and inflammatory diseases has been .
研究人员已经提出对自体免疫与炎症性疾病中TLR介导的通路进行深入研究。
The involvement of TLR-mediated pathways in autoimmune and inflammatory diseases has been .
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