目的检测植物血凝素及淋巴因子激活的杀伤细胞(PHA -LAK)的体外广谱抗肿瘤作用。
Objective to detect the in vitro antitumor action of phytohemagglutinin and lymphokine activated killer (PHA-LAK) cells.
目的:采用无血清培养体系,研究CD 3单克隆抗体激活的杀伤(CD3AK)细胞诱导HL6 0细胞凋亡情况。
Objective: to investigate whether CD3McAb activated killer (CD3AK) cells could induce apoptosis in HL 60 cells in serum free culture system.
目前认为,经激活的巨噬细胞释放的NO可以通过抑制靶细胞线粒体中三羧酸循环、电子传递和细胞DNA合成等途径,发挥杀伤靶细胞的效应。
At present, we consider NO released by activated macrophages can kill target cells by restraining the tricarboxylic acid cycle, electron transfer and composition of DNA in target cells.
结论经卵巢癌细胞冻融抗原负载dc激活的CTL在体外具有更强的增殖能力和杀伤卵巢癌细胞的作用。
Conclusion CTL activated by DC loaded with freeze-thaw ovarian carcinoma antigen has a higher proliferative ability and effective cytotoxicity against ovarian carcinoma cells in vitro.
及NO是激活的巨噬细胞杀伤肿瘤细胞的主要效应分子。
TNF-a and NO are two major tumorcidal effector molecules of activated macrophages.
目的:研究肺癌清扫淋巴结的淋巴细胞,经CD 3单克隆抗体激活后的杀伤细胞(CD3AK细胞)在体外的增殖和表型变化。
Objective: To study the propagation and phenotypes changes of killer cell CD3AK cell activated by CD3 mAb in vitro.
目的:cd3ak细胞是由抗cd3单克隆抗体和IL 2共同激活诱导的肿瘤杀伤细胞。
Objective: CD3AK cells were tumor-killing cells induced by costimulation of anti-CD3McAb and IL-2.
结论:放疗能部分激活CD8+T及NK细胞介导的杀伤免疫,同时抑制T细胞和NK细胞的分化及其信号传导通路。
Conclusion: The conventional fractioned radiotherapy can activate cell mediated immunity of CD8+ T and NK cells, but inhibit the differentiation of T cells and NK cells signaling transduction pathway.
结论:放疗能部分激活CD8+T及NK细胞介导的杀伤免疫,同时抑制T细胞和NK细胞的分化及其信号传导通路。
Conclusion: The conventional fractioned radiotherapy can activate cell mediated immunity of CD8+ T and NK cells, but inhibit the differentiation of T cells and NK cells signaling transduction pathway.
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