为研究氢化酶活性中心氮桥结构中氮原子是否起到质子摆渡的作用,设计了在分子内引入氢键的结构。
To explore the role of the bridged N atom for a possible proton transfer in the active site of hydrogenase, we tried to introduce a hydrogen bond into a couple of designed molecules.
他们也设计了一个特殊的抑制物(小分子),它可以结合在人类DDAH的活性位点上。
They also designed specific inhibitors (small molecules) which bind to the active site of human DDAH.
该研究为进一步理解磺酰脲类的分子结构、药物活性并设计新的分子提供了帮助和指导。
This study will provide assistance and guidance to further understand molecular structure of sulfonylurea and its herbicidal activity and to design new compounds.
目的:筛选并鉴定与人CD59分子特异结合的短肽,为设计具有拮抗CD59肿瘤逃逸活性的短肽封条奠定基础。
AIM: To screen and identify the short-peptide which specifically bind to human CD59 so as to design short-peptide clamp with counteracting tumor escape activity.
对大分子前药的设计与合成,载体、活性药物和连接基的选择进行了论述。
The design and synthesis of macromolecular prodrugs, choice of polymer carrier, active drug and linker are introduced.
研究目的是分子设计并构建较G-CSF单体分子具有半衰期更长、生物活性更高的新型重组人G-CSF/G-CSF双体分子(简称G-G),并在原核系统进行高效表达。
Molecule design, construction and high level expression in E. coli. of bimolecular G-CSF with longer half life and higher bioactivities than single molecular G-CSF.
而该聚合物和表面活性剂分子结构的设计与优化对提高二元复合驱油体系性能的影响还有待研究。
But how the molecules structure design and optimization of polymer and surfactant would improve the binary oil-displacing system remains to be seen.
为了能寻求一种切实可行及表达高活性小分子ngf的生产途径,我们通过基因工程和细胞工程技术设计了两种NGF的体外重组方案。
To look for a good method to producing NGF which has low molecular weight, we designed two projects which are carried out through gene cloning and cell engineering techniques to provide the problem.
设计合成了含有活性基-羧基、氨基、羟基的尼罗红和尼罗兰衍生物,用来标记生物分子。
Nile red and Nile blue derivatives with carboxyl or amino or hydroxyl group were synthesized, which were used to tag biological molecules.
设计合成了含有活性基-羧基、氨基、羟基的尼罗红和尼罗兰衍生物,用来标记生物分子。
Nile red and Nile blue derivatives with carboxyl or amino or hydroxyl group were synthesized, which were used to tag biological molecules.
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