目的：阐述治疗药物监测的必要性和测定技术。
OBJECTIVE: to review the principles of therapeutic drug monitoring (TDM) and the role of analytical techniques in TDM.
目的：总结治疗药物监测在精神科应用的临床经验。
Objective: to evaluate the USES and procedures of therapeutic drug monitoring in clinical treatments.
治疗药物监测不应作为调整西罗莫司治疗的唯一根据。
Therapeutic drug monitoring should not be the sole basis for adjusting sirolimus therapy.
本法准确、灵敏，适用于治疗药物监测和药动学研究。
The method can be used for monitoring and pharmacokinetics study of the drug .
目的：探讨治疗药物监测在抗癫痫药物临床治疗中的作用。
OBJECTIVE To discuss the use of therapeutic drug monitoring on antiepileptic drugs in clinical therapy.
目的：促进治疗药物监测(TDM)工作深入开展，提高临床治疗水平。
OBJECTIVE: to promote the practice of therapeutic drug monitoring (TDM) and to improve clinical treatment level.
方法简便、灵敏，可充分满足临床药理研究和治疗药物监测工作的要求。
The method is simple and sensitive enough to be used for clinical pharmacological research and therapeutic drug monitoring.
方法：根据治疗药物监测的一般流程，运用数据库程序设计技术编制应用软件。
METHODS: According to the general procedure of TDM, an application software was programmed with database programming technic.
CEFA适合于血清或血浆样品的直接进样分析，有望用于临床治疗药物监测。
CEFA is suitable for the direct analysis of plasma or serum samples and could be used in clinical therapeutic drug monitoring.
目的探讨利用手指血取样代替静脉血对卡马西平进行TDM(治疗药物监测)的可能性。
Objective Explore the possibility of finger-prick blood being monitored for therapeutic drug monitoring (TDM) of carbamazepine (CBZ) instead of venous blood.
目的：采用反相高效液相色谱法测定两性霉素B的血药浓度，用于该药的治疗药物监测。
OBJECTIVE:To establish a reversed-phase HPLC assay to monitor the plasma concentration of Amphotericin B.
本文主要从新药研发和临床治疗药物监测这两个方面综述了定量药理学国内外研究进展。
This paper reviewed the advances of pharmacometrics employed in new drug research and development and therapeutic drug monitoring both at home and abroad.
结论：在丙戊酸治疗药物监测中，要关注影响丙戊酸血药浓度的因素，确保患者用药安全有效。
CONCLUSION: in therapeutic drug monitoring of valproate, it should be concerned about the impact factors of valproate concentration to ensure the safety and efficacy in patients.
结论：治疗药物监测结果需结合患者病情与临床疗效综合判断，方能实现个体化给药这一目的。
Conclusion: Individualized medication can only be achieved on account of an overall judgment involving therapeutic drug monitoring results, patient conditions and clinical efficacy.
前言： 目的：建立治疗药物监测（TDM）数据管理系统，借助网络实现数据的远程访问。
OBJECTIVE:To set up data management system for therapeutic drug monitoring(TDM), and to realize the remote database access by means of network.
其目的是为新药研究和治疗药物监测中研究药物-蛋白结合作用提供简单、耐用、易操作和可行的方法。
The purpose was to provide simple, robust, easy to implement and feasible approaches for drug-protein binding study in new drug design and therapeutic drug monitoring (TDM).
近年来定量药理学中涉及的模型化和仿真预测在新药研发、治疗药物监测和临床个体化用药等方面得到了广泛的重视和研究。
Pharmacometrics has been widely valued for its utility of modeling and simulation in drug research and development, therapeutic drug monitoring and individualized therapy.
结果：338例用药存在不同程度的问题，主要表现在联合用药、药物配伍、抗生素应用、个体化给药与治疗药物监测方面。
Results: The problems of drug use were presented, such as improper drug combinations, drug incompatibility, irrational use of antibiotics and low level of drug monitoring.
结论该方法快速、敏感、简便，对癫痫的治疗提供了可靠的实验室数据，本研究提示在癫痫治疗过程中进行治疗药物监测是非常必要的。
Conclusions This method is fast, sensitive, simple and gives reliable laboratory data. This study indicates that in the course of treatment of epilepsy it is very necessary to monitor treatment drugs.
遵循临床治疗准则，谨慎选择药物并监测和评估实施处方疗效，可有助于改善卫生保健质量。
Careful selection of medicines, linked with clinical treatment guidelines and monitoring and evaluation of prescribing can contribute to better health care.
他还补充道，在药物及手术治疗的同时，进行等待观察，或者症状监测，对这些人来说是很好的选择。
Watchful waiting, or monitoring symptoms while holding off on medical or surgical treatments, is a reasonable plan for these men, he added.
由此表明，TPOFF可作为一种具有很小侵袭性的系统被用于识别肿瘤标记物和监测药物治疗。
These results suggest TPOFF can be used as a minimally invasive system for identifying tumor markers and monitoring drug therapy.
高血压是一种以慢性血压增高为特征的疾病，必须通过药物治疗、改变生活方式或两者联合来监测、治疗和控制高血压。
Hypertension is a disorder characterized by chronically high blood pressure. It must be monitored, treated and controlled by medication, lifestyle changes, or a combination of both.
对治疗期间可能出现的药物使用必须连续监测。
Possible drug use during treatment must be monitored continuously.
结论：疏血通注射液对急性缺血性脑卒中的微栓子具有预防和治疗作用；tcd栓子自动监测有助于及时发现微栓子、评估药物疗效。
CONCLUSION: Shuxuetong injection has preventive and therapeutic effects on MES of AIS, TCD automatic embolus monitor helps to find MES in time and evaluate the effect of drugs.
然而，变化的医疗和牙科技术需要我们大家来监测的效力，都建立和新的治疗药物。
However, changes in medical and dental technologies require all of us to monitor the effectiveness of both established and new treatments.
绘制糖胺聚糖的浓聚图除了可以确定药物治疗的功效外，还可以帮助诊断和监测许多疾病。
Mapping the GAG concentration is necessary for the diagnosis and monitoring of a number of diseases as well as to determine the efficacy of drug therapies.
纳米微粒在癌症的监测、治疗，细胞和蛋白质的分离，基因治疗，靶向和缓释控药物等中都有着广泛的应用。
Nanobiomaterials can be widely used in the fields of monitoring and therapy of cancer, separation of cells or proteins, genic therapy, drug target delivery and release, and so forth.
结论抗精神病药物可导致精神分裂症患者肝功能异常，在治疗精神分裂症患者期间应定期监测肝肾功能。
Conclusion Antipsychotics may interfere with liver and renal functions, so that regular monitoring of liver and renal functions is recommended during antipsychotic treatment.
结论抗精神病药物可导致精神分裂症患者肝功能异常，在治疗精神分裂症患者期间应定期监测肝肾功能。
Conclusion Antipsychotics may interfere with liver and renal functions, so that regular monitoring of liver and renal functions is recommended during antipsychotic treatment.
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