目的寻找活性强、副作用小的5 -氨基水杨酸衍生物。
Objective To search a better 5-aminosalicylic acid (5-asa) derivative with higher activity and less side effects.
5氨基水杨酸的最佳每日总剂量和剂量频率仍有待确定。
The optimal total daily dose and dose frequency of 5-asa remain to be determined.
结论采用合适的片芯和包衣，可制备5氨基水杨酸肠溶定时释放片。
CONCLUSION 5 ASA Enteric time controlled released tablets can be prepared by using adequate core and coating.
比较直肠5氨基水杨酸和安慰剂或其它积极治疗的随机试验都被纳入。
Randomized trials comparing rectal 5-asa to placebo or another active therapy were eligible for inclusion.
目的制备5氨基水杨酸(5ASA)肠溶包衣片，使药物在结肠释放。
OBJECTIVE To prepare the 5 aminosalicylic acid (5 ASA) enteric time controlled released tablets with site specific drug delivery in colon.
方法观察25例克罗恩病患者中氨基水杨酸制剂、糖皮质激素及手术治疗的疗效。
Methods 25 cases of Crohn's disease were retrospectively collected and the effects of treatment by aminosalicylic acid and glucocorticoid and operation was respectively studied.
以对氨基水杨酸为原料，经酯化、酰化和烃化反应得乙氧苯酯，总收率为87.4%。
Ethopabate is prepared via esterification, acylation and alkylation from p-aminosalicylic acid in87.4% overall yield.
对于轻度至中度活跃的远端溃疡性结肠炎病患，直肠5氨基水杨酸应被视为第一线治疗。
Rectal 5-asa should be considered a first-line therapy for patients with mild to moderately active distal UC.
目的：用水分散体包衣技术制备5氨基水杨酸(5 ASA)结肠定位释放小丸给药系统。
Objective: To prepare 5 ASA colon specific targeting pellets by using aqueous dispersion coating process.
口服后易在肠内分解为磺胺吡啶及5-氨基水杨酸，对结肠壁组织有亲合力，起到消炎作用。
Hind of profess to convinced is easy decompose inside bowel reach 5 - amino salicylic acid for sulphanilamide pyridine, to colonic wall the organization has affinity, have antiphlogistic effect.
三年前，英国研究者报告将链霉素和另一种更新的药物——对氨基水杨酸联合应用可以减少耐药性的发生。
Three years earlier, researchers in Britain reported that combining streptomycin with a newer medicine, para-aminosalicylic acid, could reduce the development of drug resistance.
建立了高效液相色谱-电化学检测法测定美沙拉秦中有关物质3 -氨基水杨酸、2 -氨基苯酚和4 -氨基苯酚。
HPLC method with electrochemical detection was established for the determination of the related substances-3-aminosalicylic acid, 2-aminophenol, 4-aminophenol, in mesalazine.
建立了高效液相色谱-电化学检测法测定美沙拉秦中有关物质3 -氨基水杨酸、2 -氨基苯酚和4 -氨基苯酚。
A HPLC method with electrochemical detection was established for the determination of the related substances-3-aminosalicylic acid, 2-aminophenol, 4-aminophenol, in mesalazine.
方法以水杨酸为起始原料，通过硝化、酰化、卤化反应，与对乙酰氨基酚相偶联，合成了新的5 -氨基水杨酸衍生物。
Methods By the reactions of nitration, acylation, halogenation, condensation, a new 5-aminosalicylic acid derivative was synthesized from salicylic acid and acetaminophen.
研究了两种聚苯乙烯树脂对水中磺基水杨酸的吸附行为，同时探讨了氨基修饰聚苯乙烯树脂的吸附动力学特性。
The adsorption of sulfosalicylic acid on two hypercrosslinked polymeric adsorbents from water was studied. The adsorption kinetic of amino modified polystyrene was also investigated.
研究了两种聚苯乙烯树脂对水中磺基水杨酸的吸附行为，同时探讨了氨基修饰聚苯乙烯树脂的吸附动力学特性。
The adsorption of sulfosalicylic acid on two hypercrosslinked polymeric adsorbents from water was studied. The adsorption kinetic of amino modified polystyrene was also investigated.
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