结论QT VI技术联合经胸超声心动图可有效地监测评估阿霉素早期心脏毒性模型的建立和效果。
Conclusions QTVI and transthoracic echocardiography are valuable to assess adriamycin-induced early myocardial damage model in rabbits.
目的探讨应用定量组织速度成像(QTVI)技术联合经胸超声心动图评价阿霉素早期心脏毒性模型建立的价值。
Objective To evaluate quantitative tissue velocity imaging (QTVI) and transthoracic echocardiography in detecting early adriamycin-induced myocardial damage model in rabbits.
在蠕虫模型中发现了几种其他化合物可以减轻蛋白质毒性。
Several additional compounds were shown to alleviate proteotoxicity in worm models.
如条件适宜(如，使用新型佐剂)，应利用动物模型开展生殖毒性研究。
Where appropriate (e.g. with use of novel adjuvants), reproductive toxicity studies using animal models should be conducted.
它表现出了对肿瘤细胞有毒性而对正常细胞则无，并且这种药物对乳腺癌和黑色素瘤的细胞及动物模型的已经表现出了治疗有效性。
These have been shown to be toxic to cancer cells and not to normal cells, and have already been shown to effectively treat cellular and animal models of breast cancer and melanoma.
然后再以雄性大鼠为模型全面研究DEX的诱导效应和诱导机制，以及DEX诱导后CPA毒性改变的各种表现。
It was scrutinized then the profiles and mechanisms of DEX induction, and the changes of CPA toxic manifestations after DEX induction.
这一结果支持了生物配体模型（BLM）概念的假设，说明在胚胎的表面，铅离子与钙离子可能在传输和毒性作用位点上存在竞争作用。
And the aim of the study was to investigate the extent to which calcium can individually mitigate lead ion toxicity based on the concept of biotic ligand model(BLM).
体外肝细胞模型(主要是原代肝细胞培养)作为一种强有力的体外研究体系被广泛应用于化学异物的肝毒性研究。
In vitro liver cell models (mainly primary hepatocyte cultures), served as the most powerful in vitro research system are widely used for the study of hepatotoxicity of xenobiotics.
当我们用传统静态培养和我们的新模型，对比肾脏功能和药物毒性的时候，我们发表细胞表现的显著差异。
When we compared physiological renal function and drug toxicity in traditional static culturing against our new model, we found significant differences in the ways that cells behaved.
为探讨高压氧对药物性聋的影响及其临床意义，对60只庆大霉素中毒性聋豚鼠模型进行了研究。
Studying the effect of hyperbaric oxygen to cochlear deafness and its clinical meaning by researching 60 guinea pigs which had toxic deafness induced by gentamicin.
以鸡胚肢软骨为氟中毒模型，通过鸡胚肢软骨细胞超微结构观察，研究了氟对鸡胚软骨细胞的毒性作用及镁对其作用的拮抗效应。
In this paper, the fluorine toxicity on limb cartilage cells of chick embryo and the dose-response relationship were studied. Meanwhile the ultrastructures of the cells were also observed adding Mg.
方法：采用大肠杆菌内毒素复制大鼠内毒性热瘀证模型基础上，检测桃核承气汤对血液流变学和凝血指标的影响。
Method: Take Bacillus Coli endotoxin to copy rats endotoxic heat - stasis syndrome model, then test the effect of PRC on rheology and coagulation indexes.
在今后的研究中，如何改善肝脏体外模型的培养条件及完善药物肝脏毒性研究体系是急需解决的课题。
For the future, there is a need for better culture conditions and more complete system of the drug toxicology research.
目的建立一个简便易行的动物模型及细胞毒性T细胞(CTL)检测体系，为HCV感染中ctl作用研究奠定理论基础。
Objective to establish a simple animal model and the cytotoxic t cell (CTL) detecting system for the studies of the effects of CTL on HCV infection.
目的探讨庆大霉素诱发的中毒性急性肾小管坏死动物模型的建立，研究其在基础及临床科研中的价值。
Objective to discuss the foundation of the animal model of gentamicin-induced toxic acute tubular necrosis and approach its value scientific research.
经过7个预测样本对该模型进行验证，结果表明该模型具有很好的预测能力，并分析了苯胺类化合物的毒性机理。
The model has a good forecasting ability for other 7 compounds. And the toxic mechanism of the aniline compounds was also analyzed.
报告称，小组已经测试了此修正化合物在动物模型包括大鼠，狗和猴子中的作用，确保其无毒性。
The group, the report says, has already tested this modified version in animal models, including rats, dogs and monkeys, to make sure it is not toxic.
采用广义加性模型分析患者营养状况和急性放射毒性的关系。
Relationships between nutritional status and acute radiotoxicities were analyzed by generalized additive models.
目的建立化学发光法检测药物光毒性的模型。
Objective to establish a test model for phototoxic agents with the method of chemiluminescence.
将模型用于23种取代苯类有机物的生物毒性预测，结果满意。
The QSAR-ANN model has been used to predict the bio-toxicity of 23 substituted benzene chemicals.
目的建立慢性酒精中毒性肌病的动物模型。
Objective To establish an animal model of chronic alcoholic myopathy in rats.
目的：建立一种可靠、实用的复发性单疱病毒性角膜炎（HSK）的实验模型。
To establish a reliable and practical model of recurrent herpes simplex keratitis (HSK) in mouse.
探讨终末期肝病模型(MELD)评分系统对预测慢性重型乙型病毒性肝炎患者短期预后的临床应用价值。
To assess the value of the model for end-stage liver disease (MELD) on the short-term prognosis in the patients with chronic liver failure (chronic and severe hepatitis B).
目的：旨在探讨冬虫夏草提取液早期治疗病毒性心肌炎小鼠模型的疗效。
Objective:To investigate the effects of cordyceps sinensis alcohol extractive on viral myocarditis.
因此，对越来越多的新化合物的毒性进行方便、快捷和准确的预测就显得十分必要，化合物预测模型的构建在毒理学研究中具有良好的应用前景。
Today it is necessary to estimate new chemicals conveniently, quickly and precisely. The warning model of chemicals in toxicology has a favorable prospect of application.
用固定床连续流动微反装置，以苯加氢为模型反应考察了催化剂的加氢性能、热稳定性及抗硫毒性。
Hydrogenation activity, heat resistance, anti poisoning ability for benzene hydrogenation were determined in a microreactor GC system.
树突细胞作为免疫毒性评价模型还可以弥补现有的免疫毒性评价环节的缺失以及为自身免疫反应评价提供突破点。
This also can compensate for the current absence of immunotoxicity evaluation process and offers new approaches to the autoimmune responses.
树突细胞作为免疫毒性评价模型还可以弥补现有的免疫毒性评价环节的缺失以及为自身免疫反应评价提供突破点。
This also can compensate for the current absence of immunotoxicity evaluation process and offers new approaches to the autoimmune responses.
应用推荐