每6个月使用扩展残疾状态量表对所有患者进行一次临床评估，并在研究开始时以及4年中每年进行一次MRI评估。

All patients were clinically assessed by means of the Expanded Disability Status Scale every 6 months and underwent MRI evaluation at study entry and then annually for 4 years.

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每6个月使用扩展残疾状态量表对所有患者进行一次临床评估，并在研究开始时以及4年中每年进行一次MRI评估。

All patients were clinically assessed by means of the Expanded Disability Status Scale every 6 months and underwent MRI evaluation at study entry and then annually for 4 years.

youdao