这会比核酸外切酶测序法快得多。
这会比核酸外切酶测序更快,也会更加精确:因为碱基彼此间仍然相连,不会以错误的顺序通过纳米孔。
It would also be more accurate: because the bases are still attached to one another, there is no chance that they will pass through the nanopore in the wrong order.
所以“牛津纳米孔公司”,和快速测序领域的领头羊,“Illumina公司”也在一同研究一种叫做“核酸外切酶测序”的办法。
So Oxford Nanopore has also been looking at an alternative approach, called exonuclease sequencing, in conjunction with Illumina, an American firm that is the market leader in rapid sequencing.
就牛津大学的纳米孔技术而言,DNA分子依靠第二种蛋白质以一次一个碱基的速度通过小孔。这个蛋白质是一种被称为核酸外切酶的酶。
In the case of Oxford Nanopore's technology, the DNA molecule is fed through the hole one base at a time by a second protein, an enzyme called an exonuclease.
取而代之一种叫做“核酸外切酶”的酶类被附着在AHL的顶部,它从DNA链上劈开各个碱基对,然后把它们填进孔道内,以供一个一个地识别。
Instead an enzyme, called an exonuclease, is attached to the top of the AHL. It cleaves individual base pairs from the DNA strand and feeds them through the pore to be detected one at a time.
桑赫拉博士说“牛津纳米孔公司”已经发明出了一个基于“片上实验室”技术,叫做“网离子”的电子模块系统,用来核酸外切酶的测序。
Dr Sanghera says Oxford Nanopore has developed an electronic cartridge system called GridION, based on "lab on a chip" technology, for exonuclease sequencing.
本专利提 出了一种检测转录因子表达和活化水平的新方法“核酸外切酶III消化微孔板包被特殊标记双链核酸分子检测转录因子蛋白”。
The present invention proposes exonuclease III digesting double stranded nucleic acid molecule coated in microporous plate and containing special marker to detect transcription factor protein.
本专利提 出了一种检测转录因子表达和活化水平的新方法“核酸外切酶III消化微孔板包被特殊标记双链核酸分子检测转录因子蛋白”。
The present invention proposes exonuclease III digesting double stranded nucleic acid molecule coated in microporous plate and containing special marker to detect transcription factor protein.
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