结论:卵巢癌组织中MIF蛋白表达上调导致巨噬细胞和自然杀伤细胞增多,可能是肿瘤进一步恶化的原因之一。
Conclusion the up-regulated expression of MIF can make the increase of macrophages and natural killer cells, it is one of the reasons of tumor development.
目前认为,经激活的巨噬细胞释放的NO可以通过抑制靶细胞线粒体中三羧酸循环、电子传递和细胞DNA合成等途径,发挥杀伤靶细胞的效应。
At present, we consider NO released by activated macrophages can kill target cells by restraining the tricarboxylic acid cycle, electron transfer and composition of DNA in target cells.
巨噬细胞对钩体具有吞噬和杀伤作用,同时,致病性钩体可逃避巨噬细胞杀伤。
Macrophages can phagocytize and kill leptospira, while the pathogenic leptospira can evade the killing by macrophages.
推测系因雌性小白鼠对瘤细胞的抑制或杀伤作用较雄性更多依赖(直接或间接)于巨噬细胞的机能之故。
The effect of defence in female mice against tumor attack dependent directly or indirectly on the function of macrophages were much greater than that in male mice.
结果:APS能促进巨噬细胞NO合成,并能显著增强小鼠腹腔巨噬细胞对黑色素瘤细胞的杀伤作用。
Results: APS could significantly increase no synthesis and enhance the effects of mice peritoneal macrophage on killing carcinoma cells.
及NO是激活的巨噬细胞杀伤肿瘤细胞的主要效应分子。
TNF-a and NO are two major tumorcidal effector molecules of activated macrophages.
测定小鼠淋巴细胞增殖功能、腹腔巨噬细胞吞噬活力和自然杀伤细胞(NK细胞)活性。
Proliferation of lymphocytes, the phagocytosis of macrophage in abdominal cavity and cytotoxicity of NK cells were determined.
该因子由肝脏中被称为自然杀伤(NK)细胞的免疫细胞释放,但是只有当另一种免疫细胞,巨噬细胞存在时才释放。
The factor was released from immune cells called natural killer (NK) cells in the liver, but only if another immune cell, the macrophage, was present.
同时段分别检测巨噬细胞吞噬功能、杀伤活性和趋化作用。
At the same time, the phagocytic function, cytotoxicity and chemotaxis of the macrophages were detected.
结论:标记抗体在体外对单核、巨噬细胞显示了相对特异的杀伤活性。
Conclusion The conjugation can show a highly specific cytotoxicity upon mononuclear-macrophage in vitro.
而BALB/C小鼠腹腔巨噬细胞吞噬率及脾脏自然杀伤细胞活性均明显高于对照组(P <0 .0 1,P <0 .0 5)。
Moreover, both murine(BALB/C mice) celiac macrophage phagocytosis and spleen natural-killer-cell activity were higher than that of the control significantly (P<0.01, P<0.05).
而BALB/C小鼠腹腔巨噬细胞吞噬率及脾脏自然杀伤细胞活性均明显高于对照组(P <0 .0 1,P <0 .0 5)。
Moreover, both murine(BALB/C mice) celiac macrophage phagocytosis and spleen natural-killer-cell activity were higher than that of the control significantly (P<0.01, P<0.05).
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