“然而,鉴于后果严重,FDA要求制造商在西布曲明的药品标签上加上新的禁忌症。”药品监督网如是说。
"However, based on the serious nature of the review findings, the FDA requested and the manufacturer agreed to add a new contraindication to the sibutramine drug label," the Medwatch alert stated.
2008年12月,FDA向消费者发出了一份警示,点名27种作为减肥营养品出售的产品非法含有不确定量的西布曲明。
In December 2008, the FDA issued an alert to consumers naming 27 products marketed as dietary supplements for weight loss that illegally contained undisclosed amounts of sibutramine.
星期三发表的所谓SCOUT研究的最终数据表明西布曲明增加已患心脏病的患者的心脏病发作和中风的风险。
Final data from the so-called SCOUT study, published on Wednesday, showed Meridia increases the risk of heart attacks and strokes in patients who already have heart disease.
目的:评价西布曲明治疗单纯性肥胖病的临床疗效和安全性,并比较西布曲明和安慰剂对静息代谢率的影响。
Objective to evaluate the clinical therapeutic efficacy and safety of sibutramine to simple obesity and compare the effects of sibutramine and placebo on resting metabolic rate.
研究表明,与接受安慰剂的患者相比,接受西布曲明患者例如心脏病发作和中风等心脏问题风险增加16%。
Patients given Meridia had a 16 percent increased risk of heart problems such as heart attack or stroke compared to those given a placebo, the study showed.
方法通过荧光法和吸收光谱法确定了盐酸西布曲明对牛血清白蛋白的荧光猝灭机制。
Methods the quenching mechanism of the fluorescence of bovine serum albumin by sibutramine hydrochloride was studied with the fluorescence and the absorption spectroscopy.
据加拿大卫生部在2008年8月18日发布的一份报告中显示,减肥药中的甲状腺激素和西布曲明会引发患者的癫痫病症。
According to health Canada on August 18, 2008 issued a report that the medicine reducing weight, thyroid hormone and sibutramine can cause of disease.
方法采用高效液相色谱法测定中药保健品中掺入盐酸西布曲明的含量,并用薄层色谱、高效液相色谱、红外光谱以及质谱技术进行定性鉴别。
METHODS an HPLC method was established to determine the contents of the organic extract of TCM preparations. Sibutramine hydrochloride was also identified by TLC, HPLC, IR and MS.
方法采用高效液相色谱法测定中药保健品中掺入盐酸西布曲明的含量,并用薄层色谱、高效液相色谱、红外光谱以及质谱技术进行定性鉴别。
METHODS an HPLC method was established to determine the contents of the organic extract of TCM preparations. Sibutramine hydrochloride was also identified by TLC, HPLC, IR and MS.
应用推荐