结论:饮食调整和运动均能诱导糖尿病大鼠的心肌抗凋亡基因的表达,饮食调整加低强度耐力运动效果尤为显著;
Conclusion:Diet and endurance training, especially diet plus low intensity exercise, can improve the expression of antiapoptotic gene in cardiac muscles of diabetic rats.
原癌基因的激活,抑癌基因的失活、突变,抗细胞凋亡等不同的机制都可能参与其中。
The different mechanisms, such as the activation of oncogenes, the inactivation and mutation of tumor suppressor gene, antiapoptosis and so on are involved in .
我们以人急性早幼粒白血病细胞株HL-60作为实验对象进行石蒜碱抗白血病作用机制研究,在凋亡相关基因表达变化和细胞周期阻滞两方面展开探讨。
We used human acute promyelocytic leukemia cell line HL-60 to study the anti-tumor mechanisms of lycorine in two aspects: apoptosis and cell cycle arrest.
其作用机制可能与调节相关癌基因及抗凋亡蛋白的表达,降低线粒体膜电位有关。
These activities of the anti-CD44 antibody may be associated with its inhibitory effect on oncogene and anti-apoptosis protein expressions, and changes in mitochondrial membrane potential.
背景与目的:肿瘤坏死因子相关凋亡诱导配体(tumornecrosisfactor-relatedapoptosisinducingligand,TRAIL)有广谱的抗瘤作用,且对正常组织细胞无毒性,因此有望应用于肿瘤基因治疗。
BACKGROUND & OBJECTIVE: Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) can induce apoptosis in various cancer cell lines with little toxicity toward normal cells.
背景与目的:肿瘤坏死因子相关凋亡诱导配体(tumornecrosisfactor-relatedapoptosisinducingligand,TRAIL)有广谱的抗瘤作用,且对正常组织细胞无毒性,因此有望应用于肿瘤基因治疗。
BACKGROUND & OBJECTIVE: Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) can induce apoptosis in various cancer cell lines with little toxicity toward normal cells.
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