方法：以吲哚-3-甲酸为起始原料，酰氯化后与托品醇锂发生缩合反应，再与盐酸成盐制得盐酸托烷司琼。
Methods tropisetron hydrochloride was synthesized from indol-3-yl carboxylic acid by chlorination and condensation with tropic alcohol lithium, then salt formation with hydrochlororic acid.
将七号位碳上的溴基取代成各种苯胺类衍生 物，再与4-甲氧基-磺基氯苯反应得到6-氮基吲哚-1-磺胺。
The 7-bromo group was replaced with various aniline, and then treated with 4- methoxybenzenesulfonyl chloride to afford the 6-azaindole-1-sulfonamides.
将七号位碳上的溴基取代成各种苯胺类衍生 物，再与4-甲氧基-磺基氯苯反应得到6-氮基吲哚-1-磺胺。
The 7-bromo group was replaced with various aniline, and then treated with 4- methoxybenzenesulfonyl chloride to afford the 6-azaindole-1-sulfonamides.
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