方法制作肾性高血压大鼠脑动脉瘤模型,系统动态观察脑动脉瘤形成过程中MMP - 2、MMP - 9及其特异性抑制物(TIMP - 1)表达的变化。
Methods a rat model of cerebral aneurysm was established. The dynamic changes of MMP-2, MMP-9 and TIMP-1 expression were examined in the process of aneurysm formation.
介绍了水合物抑制剂hbh的合成工艺,对其水合物抑制性及与其它处理剂的配伍性进行了室内评价。
In this paper, synthetic technology of hydrate inhibitor HBH is presented and its inhibitive property and compatibility with other additives are also evaluated in laboratory.
目的探讨纤溶酶原激活物抑制物-1(PAI- 1)启动子区基因多态性与脑卒中的关系。
Objective To investigate the relationship between the plasminogen activator inhibitor 1(PAI 1) promotor region gene polymorphism and cerebral stroke.
初步的研究表明:西湖沉积物中的碱性磷酸酶活性和底泥中溶解性磷的变化趋势基本一致,但高浓度的溶解性磷对APA产生一定的抑制作用;
The primary experiment shows that: The trend of APA in the sediment was coincident with the dissolved phosphorus(DP), but high concentration of DP will restrain APA to a certain extent.
软骨一直被认为是内源性血管生成抑制物的重要来源。
The mammalian cartilage has been known as an important resource of angiogenic inhibitors for a long time.
所得化合物均具有抑制A549肺癌细胞生长的活性,其抑制效果具有浓度依赖性。
These compounds were assayed for inhibitory activity against A549 lung cancer cell growth, and the inhibitory effects on the cell viability were dose-dependent.
试验结果提示:这几种中药复方提取物对仔猪腹泻的防治作用与促进水、钠向肠上皮细胞转运,抑制肠道炎性渗出及抑制小肠运动有关。
These roles of the Chinese herb extracts on the tested animals might be related to the transport of water and sodium ion from intestinal cavity to the epithelial cells of intestinal mucosa.
组织因子通路抑制物是内源性组织因子抑制物,对调剂血栓形成有重要作用。
Tissue factor pathway inhibitor (TFPI) is the endogenous inhibitor of TF and the role of TFPI is important for regulating the thrombus formation.
免疫抑制蛋白B7同系物1(B7-H1),亦称程序性死亡配体1(PD-L1)在包括癌症等许多病变中表达增高。
Expression of the immunosuppressive protein B7 homolog 1 (B7-H1), also known as programmed death ligand-1 (PD-L1), is increased in many pathological conditions, including cancer.
它们是损伤后轴索反应性生长的天然抑制物。
They serve as natural impediments to neurite growth in response to injury.
用酶联免疫吸附法检测血浆血管性假性血友病因子、凝血酶调节蛋白、纤溶酶原激活物抑制物1水平。
The von Willebrand's disease factors in plasm, adjusted protein of thrombase and inhibitor 1 of activator of plasminogen were detected with enzyme-linked immunosorbent assay.
雄蛾性附腺提取物对雌蛾性信息素合成的抑制作用与注射剂量有明显的相关性,02ME (雄蛾当量)是产生显著抑制作用的最小剂量。
There was a dose response relationship of pheromonostatic activity of male accessory gland extract, and 0 2ME (male equivalent) was the minimum dose required for effective inhibition.
结论:含硫化合物引起的正性肌力作用可能与它的酶抑制作用有关。
CONCLUSION: The positive inotropic effect on cultured myocardial cell sheets induced by sulfur compounds may be correlated with its inhibition on enzyme.
目的:观察代偿性心脏增大大鼠心肌肥厚过程中各种炎症反应标记物的动态变化及特异性环氧化酶-2抑制剂的影响。
Objective:To investigate the change of inflammation marker in the development of rats with pressure overloaded hypertrophy myocardium and influence of selective cyclooxygenase-2 inhibitor.
结果:受试物对角叉菜胶诱发的大鼠足爪肿胀、大鼠棉球肉芽肿、大鼠佐剂性关节炎均有显著抑制作用。
RESULTS:Potassium chloride glucosamine inhibited all the model inflammation. CONCLUSION:Potassium chloride glucosamine could have the effect of therapeutic arthritis.
页岩滚动回收测试结果表明共聚物的抑制性好于阴离子型AMPS共聚物。
The results of recovery of rolled shale samples show that the inhibitory property of the amphoteric copolymer is better than that of an anionic AMPS copolymer.
目的:观察荜拔油不皂化物对实验性C57BL/6小鼠胆囊结石形成的抑制作用。
Objective To explore the effect of the oil of piper longum unsaponifiablc matter(OPUM) on experimental gallstone formation in the gallbladder of C57BL/6 mice.
作为天然核苷受体的竞争性抑制剂,糖环部分化学改造的核苷类似物在过去的几十年中得到了深入的研究。
As competitive inhibitors of natural nucleoside receptors, sugar-modified nucleoside analogues have been well studied in the past few decades.
用L—酪氨酸作底物,测定了银杏叶提取物对酪氨酸酶的非竞争性抑制作用。
The noncompetitive inhibition of EGb on tyrosinase was determined with L-Tryosine substrate.
所述诊断试剂盒利用反应性复合物来方便酶或酶抑制剂的检测。
The diagnostic kit utilizes reactive complexes to facilitate the detection of the enzyme or enzyme inhibitor.
本文用支持矢量学习机和神经网络两种机器学习方法建立选择性环氧化酶-2抑制剂的活性预测模型,以期为选择性环氧化酶-2抑制剂药物的合成提供先导化合物。
Machine learning methods, including Support Vector Machines and Artificial Neural Network, are applied to the development of the classification models for the selective COX-2 inhibitors in this paper.
在肝细胞癌中,OSU-2S的抗癌效应,FTY720的非免疫抑制性类似物。
Antitumor effects of OSU-2S, a nonimmunosuppressive analogue of FTY720, in hepatocellular carcinoma.
目的:研究一氧化氮合酶抑制物非对称性二甲基精氨酸(adma)在不同因素诱发的胃黏膜损伤中的作用,并初步探讨其机制。
Objective to explore the role of endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine (ADMA) in different factors-induced gastric mucosal injury.
目的:探讨纤溶酶原激活物抑制物-1 (PAI - 1)活性变化和其基因多态性对脑梗死及其再梗死发病的关系。
To investigate the changes of plasma PAI 1 activity and its gene polymorphism in cerebral infarction.
大量研究表明,无论是有机污染物还是无机污染物,都会对AM的结构、形成和功能产生破坏性影响,主要表现在孢子萌发、侵染率、菌丝伸长受抑制等。
Both organic and inorganic pollutants could have detrimental effects on AM structure, formation and function, such as low spore germination, colonization rate, and hyphal growth.
实验显示五倍子水提取物能显著抑制胶原酶的活性,其作用呈浓度依赖性。
The experiments showed that the gallnut extract had the significant dose-dependent inhibitory effect on the activity of collagenase.
目的研究天然竹类提取物—竹醋液对致病性真菌的抑制作用。
OBJECTIVE To observe the anti pathogenic fungal actions of Distillated Bamboo acid in vitro.
这些抑制血清素能信号传递的效用可用于实施选择性的细胞杀伤和用于鉴定抑制该信号传递的化合物。
These effects of inhibiting serotonergic signaling can be useful for effecting selective cell killing and for identifying compounds that inhibit the signaling.
结果表明:这些添加物可有效地抑制镁铬砖的高温挥发,提高制品的抗渣性。
The results show: these additives can effectively control high-temperature volatilization and improve slag-resistance of magnesite-chrome bricks.
本发明能够抑制氧化物半导体层中晶格缺陷的形成并抑制湿气的进入,从而提高薄膜晶体管的可靠性。
According to the present invention, formation of lattice defect in an oxide semiconductor layer and entering of moisture can be prevented, improving reliability of the thin film transistor.
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