目的研究手性对映体d -柠檬烯和L -柠檬烯对盐酸川芎嗪透皮吸收的影响及其作用机制。
Aim To investigate the effects and permeation mechanism of D-limonene and L-limonene on transdermal delivery of ligustrazine hydrochloride (LH).
目的研究盐酸川芎嗪(TMPH)经大鼠鼻腔给药后的脑内药动学特性。
OBJECTIVE To investigate the brain pharmacokinetics of tetramethylpyrazine hydrochloride (TMPH) after intranasal administration in rats.
方法:采用盐酸川芎嗪进行鼻腔灌流实验。
Methods: The nasal circulatory perfusion test of TMP HCl was performed in rats.
目的:观察丹参粉针、盐酸川芎嗪、榄香烯乳注射液治疗恶性肿瘤高凝状态的临床疗效。
Objective:to observe effect of Danshen Injection, Tetramethylpyrazine Hydrochloride and Lemene Emulsion injection on the treatment for HCS in patients of malignant tumor.
本文选择临床上用于治疗心绞痛的药物盐酸川芎嗪(TMPH)作为水溶性模型药制备定时释药微丸。
In this paper, tetramethylpyrazine hydrochloride (TMPH), which is used for angina pectoris clinically, was selected as a water-soluble model drug to prepare timed release pellets.
与盐酸川芎嗪普通注射液对照,它们在小鼠的心、肝、脾、肺、肾组织中的分布特性有不同程度的改变,其中盐酸川芎嗪脂质体在肺组织的浓度是对照组的4.7倍。
The relative distribution percentage of LTH-liposome in lung after an iv administration was about 4.7 times as that of the LTH solution control group under the same conditions.
与盐酸川芎嗪普通注射液对照,它们在小鼠的心、肝、脾、肺、肾组织中的分布特性有不同程度的改变,其中盐酸川芎嗪脂质体在肺组织的浓度是对照组的4.7倍。
The relative distribution percentage of LTH-liposome in lung after an iv administration was about 4.7 times as that of the LTH solution control group under the same conditions.
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