缺血;再灌注;少突胶质前体细胞;nbqx。
Ischemia; Reperfusion; Oligodendrocyte precursor cells; NBQX.
结果:从大鼠少突胶质前体细胞中克隆到序列正确的GAP-43全长编码序列。
Results:The sequence of the cloned GAP-43 was confirmed to be correct by DNA sequencing.
少突胶质前体细胞培养基是专门为少突胶质前体细胞体外分化设计的最适宜的培养基。
Oligodendrocyte precursor cell differentiation medium is a complete medium designed for the differentiation of oligodendrocyte precursor cells in vitro.
目的:探讨氯化锂毛果芸香碱(匹罗卡品)致疒间大鼠早期大脑少突胶质前体细胞变化及意义。
Aim: To explore the early phase change of oligodendrocyte precursor cells in the brain of epileptic rats induced by chloride lithium-pilocarpine.
结论大鼠全脑照射后早期大脑ng2和O4表达增加,少突胶质前体细胞增多,并且和观测时间相关。
Conclusion the increase in early expression of NG2 and O4 and the number of oligodendrocyte precursor cells after whole brain irradiation of rats is related to the observation time-point.
BMP - 4在体外可抑制少突胶质前体细胞向少突胶质细胞的分化,并促使其向星形胶质细胞分化。
In vitro experiment, BMP-4 suppress oligodendrocyte precursors differentiation into oligodendrocyte and promote the astroglial differentiation.
Geron公司以前的试验表明,少突胶质前体细胞能纠正小鼠受损的运动神经元,有利于其功能的恢复。
Previous experiments carried out by Geron in rats with damaged motor nerves suggested that oligodendrocyte progenitor cells injected into the spine can redress this, helping to restore movement.
结论:氯化锂毛果芸香碱致疒间大鼠早期大脑ng2和O4表达增加,少突胶质前体细胞增多,并且和观测时间相关。
Conclusion: the early phase expression of NG2 and O4 and the number of oligodendrocyte precursor cells in the brain of epileptic rats increase and relate to the observing time-point.
结论:氯化锂毛果芸香碱致疒间大鼠早期大脑ng2和O4表达增加,少突胶质前体细胞增多,并且和观测时间相关。
Conclusion: the early phase expression of NG2 and O4 and the number of oligodendrocyte precursor cells in the brain of epileptic rats increase and relate to the observing time-point.
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