目的：通过血药浓度监测，提高对小儿急性淋巴细胞白血病大剂量甲氨蝶呤化疗的有效性和安全性。
OBJECTIVE: to improve the efficacy and safety of high dose methotrexate (HDMTX) chemotherapy in the treatment of children with acute lymphoblastic leukemia through blood concentration monitoring.
目的：通过血药浓度监测，提高对小儿急性淋巴细胞白血病大剂量甲氨蝶呤化疗的有效性和安全性。
OBJECTIVE: to improve the efficacy and safety of high dose methotrexate (HDMTX) chemotherapy in the treatment of children with acute lymphoblastic leukemia through blood concentration monitoring.
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