因此,乳腺癌多药耐药蛋白有望成为一种新的治疗靶点。
So, the breast cancer resistance protein will be the new therapeutic target.
采用流式细胞术检测骨髓细胞多药耐药蛋白P170的相对表达率,并分析P170表达阳性率与耐药性和性别间的关系。
The expression of multidrug resistance protein P170 in marrow cells was detected by flow cytometry, and the correlations of the expression of P170 with drug resistance and gender were analysed.
依赖于半胱氨酸蛋白酶的激活,美沙酮通过激活线粒体克服了白血病细胞中的阿霉素耐药、多药耐药、和凋亡抑制。
Depending on caspase activation, methadone overcomes doxorubicin resistance, multidrug resistance, and apoptosis resistance in leukemia cells through activation of mitochondria.
多药耐药相关基因与蛋白的检测。
Detection of multidrug resistance-related genes and proteins.
目的:证实抗P糖蛋白单克隆抗体(JSB1 )能逆转人肾癌的天然多药耐药(MDR)性。
Purpose:To illustrate anti P gp monoclonal antibody(JSB 1) can reverse multidrug resistance(MDR) of the human kidney cancer.
蛋白酶体抑制剂可选择性地促进肿瘤细胞凋亡,逆转多药耐药。
Proteasome inhibitors can selectively promote the apoptosis of tumor cells and overcome MDR.
结论P -糖蛋白介导的多药耐药是膀胱癌腔内灌注化疗失败、肿瘤复发的重要原因。
Conclusion the P-glycoprotein-mediated MDR may be an important cause of recurrent of bladder cancer after treated by perfusion chemotherapy.
目的综述近五年来多药耐药性p糖蛋白作用于药物肠道吸收过程的研究进展。
Objective To review the development of the key role of P-glycoprotein (P-gp) in the intestinal absorption of drugs during the past five years.
目的:建立人舌鳞状细胞癌耐放疗细胞系并检测多药耐药基因和蛋白的表达。
Objective: To establish a radiation-resistant human tongue squamous carcinoma cell line and to detect the expression of multidrug-resistant gene( MDR1) and protein (P-gp).
目的:建立人舌鳞状细胞癌耐放疗细胞系并检测多药耐药基因和蛋白的表达。
Objective: To establish a radiation-resistant human tongue squamous carcinoma cell line and to detect the expression of multidrug-resistant gene( MDR1) and protein (P-gp).
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