目的建立多色荧光原位杂交技术检测人卵细胞染色体非整倍体的方法。
Objective: To establish the method of aneuploidy detection in human oocytes by multicolor fluorescence in-situ hybridization (M-FISH).
着丝粒和端粒DNA探针多色荧光原位杂交是一种较为精确的分析微核染色体组成的方法。
Multicolor FISH with centormeric and telomeric DNA probes was a precise technique for analyzing chromosomal composition of MN.
目的探讨用多色荧光原位杂交(MFISH)技术检测的易位和双着丝粒染色体畸变的差异。
Objective To explore the differences between radiation-induced translocation and dicentric chromosome aberrations detected by multicolor fluorescence in situ hybridization (M-FISH) method.
方法：取试管婴儿助孕技术后未能受精成功的卵细胞，采用多色荧光原位杂交方法检测卵细胞13，16 ，18，2 1和2 2号染色体的情况。
Methods:Multicolor fluorescence in situ hybridization (M-FISH) was applied to check the chromosome status in oocytes for chromome 13,16,18,21 and 22.
方法：取试管婴儿助孕技术后未能受精成功的卵细胞，采用多色荧光原位杂交方法检测卵细胞13，16 ，18，2 1和2 2号染色体的情况。
Methods:Multicolor fluorescence in situ hybridization (M-FISH) was applied to check the chromosome status in oocytes for chromome 13,16,18,21 and 22.
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