胰岛素样生长因子系统在调节细胞增殖、分化与抑制凋亡中发挥重要作用。
Insulin-like growth factor (IGF) system plays an important role in regulating cell proliferation and differentiation, and inhibiting apoptosis.
结论:抑白血病因子具有抑制白血病细胞增殖和浸润的作用。
Conclusion: Anti leukemia factor have the effect of inhibitory proliferation and invasion to leukemia cell.
生长因子与酪氨酸激酶介导的信号传导有不同程度的激活,而抗增殖和免疫防御的信号传导受到不同程度的抑制,表现出一种系统复杂性的状态。
Growth factor and tyrosine kinase mediated signaling is activated and the signaling against cell proliferation is inhibited in some extent, which show a state of system complexity.
PF4属于造血负性调控因子,它抑制造血细胞增殖,但是它的这种作用是可逆的。
PF4 is a negative regulator of hematopoiesis and can inhibit hematopoietic cell proliferation but this effect is reversible.
结论含高剂量中药的大鼠血清有抑制血管内皮细胞生长因子诱导内皮细胞增殖的作用。
CONCLUSION the rat serum including high dose herb medicine could have an effect on inhibition of proliferation of endothelial cell induced by vascular ECGF.
我们发现鼠类MSC分泌高水平的IL -6和血管内皮生长因子,两者可直接抑制T细胞增殖。
We show that murine MSC secrete high levels of interleukin (IL) -6 and vascular endothelial growth factor, which are directly correlated to the inhibition of T-cell proliferation.
为维持细胞在培养过程中的未分化状态,需要采用饲养层细胞培养,同时设计合理的培养液配方并添加多种抑制分化或促进增殖的细胞因子。
Feeder layer cells and suitable culture medium that supplemented with cytokines of promoting proliferation or restraining differentiation were crucial to keep chicken es in an undifferentiated state.
结论保肾冲剂血清能抑制MC增殖并能干预活化MC分泌细胞因子。
Conclusion This study indicates that can BSM inhibited MC proliferation and intervene secretion of inflammatory medium of activated MC.
其生理作用是与破骨细胞活化因子结合,抑制破骨细胞增殖和活化,防止骨质丢失。
Its physiological function was to combine osteoclast differentiation factor, restrain the proliferation and activation of osteoclast and protect bone from losing bone mass.
结论:表皮生长因子受体抑制剂ag1487可对舌鳞癌细胞产生明显的增殖抑制作用。
Conclusion: Epidermal growth factor receptor inhibitor AG1487 may retard cell cycle, and then inhibit the proliferation of tumor cells.
大多数血管生成因子在刺激血管ec增殖和迁移的同时抑制血管EC凋亡。
Most angiogenic growth factors not only stimulate VEC proliferation and migration but concomitantly inhibit VEC apoptosis.
目的:了解表皮生长因子受体抑制剂AG1487对舌鳞癌细胞的抑制增殖作用。
Objective:To investigate the inhibitory effect of epidermal growth factor receptor inhibitor AG1487 on the proliferation of tongue cancer cells.
血管形成是实体肿瘤增殖和转移的关键步骤,这一过程依赖于内源性刺激因子和抑制因子之间的平衡。
Angiogenesis is the key step in tumors proliferation and metastasis, which depends on the net balance between endogenous stimulators and inhibitors.
另外,表面半乳糖基转移酶通过调节表皮生长因子受体信号传导能力向胞内传递生长抑制信号,在细胞增殖控制中起重要作用。
Surface GalTase also delivers a growth inhibitory signal by modulating the ability of the EGF receptor to transduce EGF dependent signals, and plays an important role during cell growth.
细胞因子信号转导抑制蛋白(SOCS)通过与受体介导的信号转导,调节细胞增殖、生长、分化及炎症发生等。
Suppressors of cytokine signaling (SOCS) associates with receptor-mediated signal transduction pathway, which can regulate cell proliferation, growth, differentiation and inflammation et al.
结论:RSV对T细胞的免疫抑制作用,可能与其抑制T细胞的活化、增殖和细胞因子的分泌有关。
CONCLUSION: The immunosuppressive action of RSV may be related with its inhibitory effects on t cell activation, proliferation and cytokine expression.
结论缬沙坦可能通过抑制巨噬细胞炎症因子表达、ROS生成及细胞增殖而发挥抗炎作用。
Conclusion The inflammation suppression roles of valsartan may be related with its effects on expression of inflammatory factors, ROS production and proliferation of macrophages.
结论:稳定表达人ox40l的乳腺癌转基因细胞在体外能有效地活化t细胞,介导其增殖、分泌细胞因子及抑制T细胞活化诱导的细胞死亡。
CONCLUSION: OX40L-MDA-MB-435 cells could activate t cells in vitro, promote t cell proliferation and cytokine secretion, and suppress t cell activation-induced cell death.
结论:稳定表达人ox40l的乳腺癌转基因细胞在体外能有效地活化t细胞,介导其增殖、分泌细胞因子及抑制T细胞活化诱导的细胞死亡。
CONCLUSION: OX40L-MDA-MB-435 cells could activate t cells in vitro, promote t cell proliferation and cytokine secretion, and suppress t cell activation-induced cell death.
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