科学家必须解决如何抑制某些部位的运动，比如恶化的肿瘤周围的细胞外基质。
Instead, scientists will have to figure out how to block movement in select locations, like in the extra-cellular matrix around growing tumors.
目的：探讨肿瘤基质血管内皮细胞的血管形成能力。
Objective: To explore the angiogenic ability of vascular endothelial cells in solid tumors.
这些肿瘤细胞产生了一整系列的蛋白酶，能降解包围它们的细胞外基质蛋白，这也是部分的基底膜。
The tumor cells produce a whole range of proteases that degrade the proteins of the extracellular matrix that hems them in, part of which is the basement membrane.
近几年来，基质金属蛋白酶因在肿瘤的生长、转移和血管生成等多个环节中发挥着重要作用而成为肿瘤治疗研究中引人注目的新靶点。
Matrix metalloproteinases (MMPs) has been viewed as a promising target in tumor therapy in recent years due to their key role in tumor growth, angiogenesis, invasion and metastasis.
背景：硫酸软骨素是细胞基质的重要成分，可促进肿瘤细胞的增殖，抑制其转移。
BACKGROUND: Chondroitin sulfate is the important component of cell matrix, it can accelerate the proliferation of tumor cells and restrain its transfer.
软骨肉瘤是产生软骨基质的恶性肿瘤。
Chondrosarcomas are malignant tumors that produce cartilage matrix.
目的：研究细胞外基质蛋白1 (ECM1)在肿瘤中的表达及临床意义。
Objective: To study the expression and clinical significance of extracellular matrix protein 1 (ECM1) in tumors.
目的：研究乳腺癌中基质金属蛋白酶-2 (MMP - 2)的表达特点，探讨其与乳腺癌生物学行为及肿瘤转移的关系。
Objective: To study the relationship between expression of matrix metalloproteinase 2 (MMP 2) and biological behaviors and tumor metastases in breast cancer.
基质金属蛋白酶(MMP)因其在肿瘤的生长、转移和血管生成等多个环节中发挥着重要作用而成为肿瘤治疗研究中引人注目的靶点。
Matrix metalloproteinases (MMPs) has been viewed as a promising target in tumor therapy due to their key role in tumor growth, angiogenesis, invasion and metastasis.
目的：探讨层粘连蛋白(LN)、基质金属蛋白酶9 (MMP 9)在卵巢粘液性肿瘤中的表达以及与临床病理因素和预后的关系。
Objective: to study the expression of laminin (LN) and matrix metalloproteinases-9 (MMP-9) and its association with clinicopathological factors and prognosis in mucinous tumors of the ovary.
但是，玻璃材质的试验器皿是唯一的选择，另外就是基质胶，是一种由大鼠肿瘤细胞产生的胶状蛋白混合分泌物。
But the only choices hae been glass labware and a product called Matrigel, a gelatinous protein mixture secreted by mouse tumor cells.
上调为主的有：细胞骨架和胞外基质、炎性应激反应、肿瘤相关、信号转导等；
Those genes with increased expression level in aging lung mainly related to cytoskeleton or extracellular matrix, inflammation or stress response, tumor, signal transduction and so on.
由于成熟的基质细胞不存在抑制肿瘤增殖的作用，我们推测可能是AFMSC的内在特性决定了这种作用的发挥。
Since the well-differentiated matrix cells don't have the inhibitory effect on tumor cell growth, we predicted that some innate features of stem cells contribute to this effect of AFMSC.
间质细胞与细胞外基质成分构成的肿瘤微环境对肿瘤细胞的生长、浸润和转移具有重要作用。
Tumor microenvironment is composed of mesenchymal cells and extracellular matrix components, which plays an important role in the growth, invasion and metastasis of tumor cells.
背景和目的：骨巨细胞瘤来源于中胚叶细胞，其肿瘤组织主要由多核巨细胞和基质细胞组成。
Background and Objective:Giant cell tumor of bone(GCT) derived from mesodermic cell, consists mostly of multinucleated giant cells and ground substance cells.
方法采用免疫组化方法检测OC、BSP、OPN在50例各型骨肉瘤肿瘤细胞、基质中的表达。
Methods Use immunohistochemistry method to detect the osteocalcin, bone sialoprotein and osteopontin expressions in tumor cells and matrix of 50 cases of osteosarcoma.
目的探讨膜型基质金属蛋白酶-1在人脑胶质瘤中的表达及其与肿瘤生物学行为和预后的关系。
Objective To investigate the expression of membrane type-1 matrix metalloproteinase(MT1-MMP) in human glioma and its relationship to clinicopathological factors and prognosis of glioma patients.
骨桥蛋白是一种具有多种功能的磷酸化糖蛋白，不仅广泛分布于骨基质等正常组织细胞中，而且在许多肿瘤组织中都过量表达。
Osteopontin is a multifunctional phosphoglycoprotein. It not only distribute widely in normal tissues such as bone tissues, but also has over expression in multiplicate tumor tissues.
目的：观察基质金属蛋白酶- 7 (MMP - 7)蛋白在鼻咽癌中的表达及与肿瘤侵袭转移的关系。
Objective: To observe the expression of matrix metalloproteinase-7 (MMP-7) in nasopharyngeal carcinoma and it's significance in metastasis.
目的探讨结直肠癌肿瘤实质及肿瘤间质中基质金属蛋白酶-2 (MMP - 2)的表达及其病理学意义。
Objective To evaluate the expression of Matrix metalloproteinase 2 (MMP 2) in colorectal tumor epithelial cells and mesenchymal cells.
下面就细胞外基质金属蛋白酶诱导因子的作用机制、调节以及与口腔颌面部肿瘤的关系作一综述。
The advanced research about action mechanism and regulation of EMMPRIN, as well as relationship between EMMPRIN and oral and maxillofacial tumors, will be reviewed in this article.
下面就细胞外基质金属蛋白酶诱导因子的作用机制、调节以及与口腔颌面部肿瘤的关系作一综述。
The advanced research about action mechanism and regulation of EMMPRIN, as well as relationship between EMMPRIN and oral and maxillofacial tumors, will be rev…
目的建立肿瘤基质血管内皮细胞模型并探讨其生物学特性。
Objective To establish the cell model of vascular endothelial cell in tumors and explore its biological features.
对骨髓瘤基质细胞打击，可直接影响骨髓瘤的生长，将是一种崭新的抗肿瘤的思路。
By affecting the growth of bone marrow stromal cell inhibit the growth of myeloma cells, that will be a brand-new anti-tumor ideas.
胃癌的侵袭和转移依赖于肿瘤间质中的血管生成和细胞外基质的降解。
The invasion and metastasis of gastric cancer depend on the angiogenesis of tumorous stroma and the degradation of extracellular matrix.
肿瘤细胞表达基质金属蛋白酶类物质和勃附分子说明了恶性黑色素瘤组织存在血管生成拟态形成的物质基础。
TIMP, MMP-2,1C AM were secreted by the tumor cells can boost the adhere of tumor cells and matrix remold and turn into the substance base of vasculogenic mimicry .
单核基质细胞中的纤维母细胞型为肿瘤的主要增殖成分，可能来自间充质。
The multinucleated giant cells do not come from a proliferating population of cells but may be a fusion product of histocyte like cells which possibly derived from the mononuclear macrophage system.
单核基质细胞中的纤维母细胞型为肿瘤的主要增殖成分，可能来自间充质。
The multinucleated giant cells do not come from a proliferating population of cells but may be a fusion product of histocyte like cells which possibly derived from the mononuclear macrophage system.
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