现在,我们可以考虑开发减弱fto基因活性的药物,用作抗肥胖药。
We can now think about developing drugs that turn down the activity of the FTO gene as potential anti-obesity pills.
研究人员还应用了单分子技术,该技术能灵敏检测基因活性。
The researchers also used a single-molecule technology that enabled them to generate sensitive readouts of gene activity.
Chang一直在使用芯片观察基因活性模式预测癌症结果。
Chang had been using the gene activity patterns of microarrays to predict cancer outcome.
同时他们采用基因活性生物发光法记录了基因的实时表达情况。
They also recorded gene expression in real - time using a bioluminescent reporter of gene activity.
在启动子区域的DNA甲基化是抑制基因活性的一种重要机制。
DNA methylation in the promoter regions is a powerful mechanism for the suppression of gene activity.
他们这些研究者还分析了大脑内的主要区域,检测两个动物每个区域的基因活性。
The researchers also dissected out major regions of the brain and measured gene activity in each region in both types of animals.
这一过程是由粘附在基因上并能改变基因活性的“化学开关”所控制的。
The process is controlled by chemical switches that stick on to genes and alter how active they are.
这项新的研究从整体上提出了一个因基因活性的不同而致结果各异的观点。
The new study gives a global view of the consequences of those differences for gene activity.
健康个体的某些短小的DNA序列上会带有甲基,做为调控基因活性的标签。
In healthy cells, certain short sequences of DNA carry methyl groups that serve as tags controlling gene activity.
如钾水平下降,膜蛋白在细菌刺激一连串的基因活性的子细胞信号形成的人数。
As potassium levels decline, a membrane protein on the bacterium stimulates a cascade of gene activity that signals neighboring cells to form a quorum.
通过比较不同脑域的基因活性,研究组证实了相应于特定大脑区域的基因网络的存在。
By comparing gene activity in different areas of the brain, the team identified gene networks that correlated to specific brain regions.
创伤后并发器官损害病人的荧光素酶报告基因活性显著高于无器官损害者,其死亡率也较高。
On the other hand, the activity of LUC was higher in the organ damagd patients than that in the non-organ damagd patients, with a high mortality rate.
了解基因活性的遗传基础将有助于医学研究从而为个体提供有关他们自身对疾病易感性的信息。
The understanding of the genetic basis of gene activity will help medical research to provide individuals with information about their personal predisposition to disease.
研究结果表明至少有10%—20%的基因活性方面的遗传变异归功于变异基因拷贝数方面的因素。
The results show that at least 10-20% of heritable variation in gene activity is due to CNVs.
研究者们发现具有PTEN基因活性降低的小鼠会导致与BRCA1突变有关联的恶性肿瘤的形成。
The researchers found that inactivating the PTEN gene in mice led to the formation of the malignant tumor associated with BRCA1 mutations.
该研究致力于揭示肝肿瘤基因活性模式与肿瘤CT扫描成像的关系,提供了一个简单的“翻译”方法。
The research process sought to reveal the relationship between genetic activity patterns in liver tumors and the tumor's appearance on ct scans, and provide a simple means of translation.
其他的工作集中在组蛋白乙酰化,这种化学修饰可以使DNA从组蛋白缠绕中解离出来,产生基因活性。
Other work has focused on histone acetylation, a chemical modification that unwinds DNA from protein spools called histones, thereby enabling gene activity.
Aaron先生跟泰晤士报说:“我们利用自然界自身调节基因活性的方法,再根据我们的目的加以改进。”
Sir Aaron told The Times: "We are taking nature's own method of regulating gene activity and exploiting it for our own purposes."
研究者发现在这样的按种族分组中,存在多于160个基因活性的显著差异,其中许多涉及到免疫系统的调节基因。
The researchers observed significant differences between racial groups in the activity of more than 160 genes, many of which were involved in regulating the immune system.
这种关闭基因的技术称为rna干扰(RNAi),目前已成为控制各物种中基因活性的一个标准方法,并在2006年获得了诺贝尔奖。
Called RNA interference (RNAi), the technique has become a standard way to control gene activity in a variety of species, earning a Nobel Prize in 2006.
他们的刊登在《自然遗传杂志上》研究,显示了在小鼠中这个基因活性的不完善可以使癌症增长减缓并且在某些情况下阻止肿瘤的发生。
Their study, published in the magazine Nature Genetics, shows that halting the activity of this gene in mice predisposed to cancer slowed the growth of — and in some cases, prevented — tumors.
辐射增强,作物叶片类黄酮含量增加、叶绿素含量降低、光合作用减弱,同时UV - B辐射诱致基因活性变化,导致DNA损伤和蛋白质含量的改变。
Enhanced UV-B radiation could increase crops' flavonoid content but decrease their chlorophyll content and photosynthesis, induce gene change, and result in DNA damage and change of protein content.
1985年Aaron先生发现了一类具有与转录因子类似功能的新的蛋白;该蛋白能够识别特定的DNA区域并且结合上去,从而导致基因活性上升或者下降。
In 1985 Sir Aaron discovered a new class of proteins that mimic this function and can recognise specific stretches of DNA and bind to them, boosting the activity of genes or damping them down.
通过双荧光素酶报告基因测定法测定了IGFBP-3对由三碘甲状腺素刺激的生长激素启动子活性的影响。
The effect of IGFBP-3 on the growth hormone promoter activity stimulated by triiodothyronine was determined by dual-luciferase reporter assay.
这种酶的其中一种功效是让艾滋病病毒处于关闭状态,因此一旦抑制了酶的活性,就反而会激活那些病毒基因。
One of their effects is to keep HIV genes switched off. So inhibiting their activity should switch those genes back on.
在最近几年里,科学家们发现特定的基因会在形成特定结构时才会有活性。
In the last few years, scientists noticed that certain genes only seem to be activated when arranged in a certain configuration.
每个阻遏物相对于另一个都失去活性,然而,两个基因永远不可能同时得到完全表达。
The repressors were designed to inactivate each other, however, such that the two genes would never be fully expressed at the same time.
每个阻遏物相对于另一个都失去活性,然而,两个基因永远不可能同时得到完全表达。
The repressors were designed to inactivate each other, however, such that the two genes would never be fully expressed at the same time.
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