伴随DNA改变的基因损伤会导致基因的点突变、染色体间基因移位和扩增性基因复制。
Genetic damage with DNA alterations leads to point mutations of genes, translocations of genetic material between chromosomes, and gene reduplication with amplification.
这种酶对阻断人类基因损伤也有十分重要的作用。”细胞分子生物学家麦克穆林说道。
This enzyme is also extremely important in counteracting damage to our genetic material, " says Mikael Molin of the Department of Cell and Molecular Biology."
看似不同的癌症诱因有一个共同点，那就是都会引起基因损伤，锁定这些开关使其处于“全开”的状态。
The common aspect of the apparently disparate causes of cancer is that they induced genetic damage, locking these switches full on.
很久以前科学就明确了吸烟会导致癌症，但是一项新研究显示儿童能从吸烟的父亲那里遗传这种基因损伤。
The science has long been clear that smoking causes cancer, but new research shows that children could inherit genetic damage from a father who smokes.
这些属性是正常细胞的基因编程功能，此举的目的是抗击感染或修复损伤。
These attributes are genetically programmed functions of normal cells that are intended to combat infection or repair injury.
有效的载脂蛋白基因通常有助于控制血流中某种脂肪的产生和活动，缺乏该种基因的动物，其脑部炎症和神经损伤会无法控制。
Animals without functioning apolipoprotein genes, which normally help control the production and activity of certain fats in the bloodstream, experienced runaway brain inflammation and nerve damage.
染色体组包涵很多基因，太多的错误复制，损伤和遗漏会导致数以万计的基因改变。
Chromosomes contain many genes, so mis-copies, breaks and omissions lead to tens of thousands of genetic changes.
几乎任何对人体或大脑造成损害的因素——基因突变，脑部损伤——都容易使人们变得更自私，不那么友善。
Almost anything that messes up your body or your brain-10 mutations, brain damage, brain injury-tends to make people more selfish and less kind.
尽管天气阴沉，山一样的工作让人不安，疑心花费数小时在Facebook网站上会损伤你的才智，但生活看起来仍很愉快——如果这样，你应该感谢你的“光明基因”。
If life looks cheery in spite of the gloomy weather, mass job insecurity and the suspicion that spending hours on Facebook is mangling your mind, you might want to thank your brightside gene.
Will (JamesFranco饰演，这次他表演得更卖力)，是一位年轻的基因工程师，在旧金山的一家生物科技公司工作。 他发明了一种可以逆转人脑损伤的血清。
Will (James Franco, trying harder than usual), a young genetic engineer working for a San Francisco biotech company, creates a serum that reverses brain damage.
欧洲的医生们现在通常用这项测试来帮助怀孕父母来确定是否需要损伤性且昂贵的基因测试，他们的后代有患罕见基因紊乱的风险。
European doctors now routinely use the tests to help expectant parents whose offspring are at risk for rare gender-linked disorders determine whether they need invasive and costly genetic testing.
另一项研究发现缺少骨桥蛋白基因的小鼠不易出现肝损伤。
Another showed that mice lacking the osteopontin gene developed less hepatic injury.
基于该技术设计的首批靶向基因的药物已经在美国开始临床试验了，主要是针对具有动脉疾病和由糖尿病引发的神经损伤的病人。
The first drugs designed to target the genes have begun clinical trials in the United States on patients with arterial disease and diabetes-induced nerve damage.
显示出的是与损伤后T细胞功能紊乱相关的成百上千的基因和蛋白的功能图，以及它们在信号通路中的配体。
What emerged was a map of the likely functions of hundreds of genes and proteins related to T cell post-trauma dysfunction, and their likely partners in signaling pathways.
筛选新的药物靶点可以通过抑制HBV复制必需的一个基因或者保持HBV所引起的AT R损伤途径中的一种失调反应。
We have designed a strategy to select new drug targets that inhibit a cellular gene required for HBV replication or restore a response stalled by HBV in the ATR DNA damage pathway.
利用手边的这些纯样，研究者应用微阵列技术生产出一系列在大面积损伤时发生改变的基因。
With pure samples in hand, researchers used microarray technology to generate a long list of genes that change when a person undergoes massive trauma.
雌性野生种小鼠的丙氨酸转氨酶是基因敲除鼠的4倍，这提示肝损伤的存在；
Female wild-type mice on an ethanol-rich diet had 4 times as much alanine aminotransferase (ALT), indicating liver injury, than mice lacking the osteopontin gene.
然后通过基因信息数据库跑出那一系列基因，查出损伤中发生改变的基因哪些是文献中列出了对T细胞功能起作用的基因。
They then ran that list through a database of genetic information to see which of the genes changed by trauma were listed in the literature as having a role in t cell function.
在此，我们研究了用白介素(IL) - 13进行腺病毒载体基因治疗的效果，白介素(IL) - 13是一种在急性肾移植损伤中有强大免疫调节特性的细胞因子。
Here we investigate the effects of adenovirus-mediated gene therapy with interleukin (IL) -13, which is a cytokine with strong immunomodulatory properties, on acute renal allograft injury.
虽然药物性肝损伤的确切机制尚不清楚，但研究人员认为，是否出现肝损伤与患者的个体基因有关。
Although the exact mechanism of DILI is unknown, research suggests that a person's genes contribute to their likelihood of developing the injury.
他们表示，越来越多的证据证实损伤，以及下一代畸形和基因突变的风险，其中包括儿童期癌症以及不育。
They say that growing evidence links the damage with the risks of defects and mutations in offspring, including childhood cancer and infertility.
支持这种关系的证据是需要修复的特定基因的损伤产生疾病例如加速衰老。
One line of evidence supporting the connection is that defects in certain genes needed for DNA repair produce maladies that mimic those of accelerated aging.
这些基因分别与细胞增殖、基因转录、凋亡、信号转导、DNA损伤修复、肿瘤分化和浸润转移及细胞周期调节等相关。
These genes were involved in cell proliferation, gene transcription, apoptosis, signal transduction, DNA damage and repair, tumor differentiation and metastasis, cell cycle, and so on.
背景与目的脑缺血损伤后细胞凋亡受诸多基因调控。
Background and objective: Many genes modulate the neuronal apoptosis following ischemia brain damage.
研究表明，两种基因与大脑炎症损伤相关，同居小鼠MAC - 1和胶质纤维酸性蛋白(GFAP)下降。
The study showed that two genes associated with damaging inflammation in the brain MAC-1 and glial fibrillary acidic protein, or GFAP showed decreased activation in the socially housed mice.
研究表明，两种基因与大脑炎症损伤相关，同居小鼠MAC - 1和胶质纤维酸性蛋白(GFAP)下降。
The study showed that two genes associated with damaging inflammation in the brain MAC-1 and glial fibrillary acidic protein, or GFAP showed decreased activation in the socially housed mice.
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