测定工程细胞株基因拷贝数是细胞生物学特性鉴定的一个方面。
We determine the copy number oft -PA gene for the cell line.
巧合的是,银屑病论文提到近期一项研究将SLE与补体蛋白c4基因拷贝数低联系起来。
Coincidentally, the psoriasis paper mentioned a recent study that linked SLE to low copy number of complement C4 genes.
他认为,“基因拷贝数异变在各类精神病症中有很大作用,我们正在努力了解其运行机理。”
"We are moving in a direction where CNVs are playing a role in a number of different neurobehavioral conditions," Cuccaro said.
EGFR基因拷贝数的改变和突变有很大的差异,科学家试图定义其在三阴性乳腺癌中的预后意义。
EGFR gene copy number alteration and mutation are highly variable and scientists have been challenged to define their prognostic significance in triple-negative breast cancer.
研究结果表明至少有10%—20%的基因活性方面的遗传变异归功于变异基因拷贝数方面的因素。
The results show that at least 10-20% of heritable variation in gene activity is due to CNVs.
我们进行此项研究,确定这类肿瘤中是否有EGFR基因的突变、EGFR基因拷贝数的增多、及ALK的易位。
We undertook this study to determine whether EGFR mutations, increases in EGFR copy number, or ALK translocations are present in these tumors.
Cuccaro说,他不认为基因拷贝数异变针对ADHD本身有很大作用,而是更容易导致ADHD的并发精神疾病。
Cuccaro said he doesn't think a given CNV is specific to ADHD but rather that the effects of a CNV are more likely to result in ADHD plus intellectual disability.
人类基因组单体型图在检测在许多疾病涉及的基因变异方面的作用不言而喻并且这些结论也表明变异基因拷贝数指数也有类似的作用。
The HapMap has been invaluable in detecting variants involved in many diseases and these results suggest that the CNV index will prove similarly useful.
在侵袭性脑胶质瘤中,表皮生长因子受体基因拷贝数更高,而且一半的侵袭性脑胶质瘤伴有一个GEFR突变。这个突变增加了肿瘤的生长,伴随一个糟糕的预后效果。
In aggressive gliomas, extra copies of the EGFR gene are produced, and half of such tumors also carry an EGFR mutation, which ramps up tumor growth and portends a poor prognosis.
研究人员发现,在个子比较矮的人身上,会出现低发生率拷贝数变异过剩——部分基因组缺失。
And the researchers found an excess of low frequency CNV deletions - where part of the genome is missing - in shorter people.
人类基因组拷贝数变异缺失在数量上也有很大的不同,有些人的缺失数甚至能达到几百万。
There is a wide variation in the amount of these CNV deletions which people have in their genome, with some people having several million.
而且,研究人员在2007年对遗传学的先驱克雷格·文特尔(J . Craig Venter)的基因组测序发现有62个拷贝数变化。
And in 2007 researchers sequenced the genome of genetic pioneer J. Craig Venter and found 62 copy number variations.
DEFB基因产物是小分子抗菌肽,且拷贝数变化(CNV)可显著影响易感性及炎症反应。
DEFB gene products are small antimicrobial proinflammatory peptides, and copy number variation (CNV) could reasonably influence susceptibility to infection and inflammation.
而那项昂贵试验检测血中病毒负荷或病毒基因的拷贝数。
The more expensive test samples the blood for viral load, or copies of viral genomes.
这些缺失或者是重复,也被称做是拷贝数的改变,能改变一个基因的数目。
These deletions or duplications, also called copy-number changes, can change the dosage of a gene.
方法采用半定量pcr方法检测了我国四种小型猪内源性逆转录病毒基因的拷贝数。
Methods Semi-quantitative PCR method was used in this research to estimate PERV copy-number of four mini-pigs in China.
基因组中一个特定基因的拷贝数。
Gene dosage — the number of copies of a particular gene in the genome.
本研究旨在筛选支气管上皮细胞恶性转化过程中拷贝数扩增的基因。
To screen amplified genes in the malignant transformation of bronchial epithelial cells.
方法获取10例淋巴瘤患者的活检淋巴结组织,以CGH技术检测淋巴瘤基因组d NA拷贝数的变化。
Methods Biopsy specimens of lymph nodes were obtained from 10 cases of lymphoma patients. The changes of DNA copies number (e. g. deletion and amplification) were detected using the CGH technique.
用户能够通过查询特定临床样品特征或个别基因的拷贝数变化构建定制的数据集。
Users can build custom datasets by querying for specific clinical sample characteristics or copy number changes of individual genes.
利用该标准质粒建立的定量方法测定了我国12种白叶枯菌株基因组中IS1112的拷贝数。
The copies of IS1112 in twelve Xoo strains from China were identified using realtime quantitative PCR with this standard plasmid.
CHS基因在裸子植物中的拷贝数较少,而在被子植物中拷贝数变化很大。
It has also been found that the gymnosperm plants have few copies of CHS gene in a particular nuclear genome, but copy number varies greatly in the angiosperm plants.
研究发现,与非多能性的细胞样品相比,具有多能性的细胞样品在亚染色体的拷贝数存在高频率的变化差异,这些变化集中在特定的基因组区域。
We report a higher frequency of subchromosomal copy number variations in pluripotent samples compared to nonpluripotent samples, with variations enriched in specific genomic regions.
胃癌中该基因表达的模板拷贝数可作为预测淋巴结转移、评价预后的一个重要指标。
It might be an important indicator in predicting lymph nodes metastasis and evaluating the prognosis.
胃癌中该基因表达的模板拷贝数可作为预测淋巴结转移、评价预后的一个重要指标。
It might be an important indicator in predicting lymph nodes metastasis and evaluating the prognosis.
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