STX107和受体结合在一起,挫伤其效率,减缓蛋白质生产到正常情况。
STX107 binds to the receptor, dampens its productivity, and slows protein production to a normal rate.
这样的受体可以是蛋白质、酶、膜通道或外来病原体的一个区域。
Thus a receptor may be a protein, enzyme, membrane channel, or a region of a foreign pathogen.
“我们惊讶地得到了死亡受体,它不会对任何激素产生反应,因为以前那些同样的状态在蛋白质中只存在很短的时间。”桑顿说道。
"We were surprised to get a dead receptor that wouldn't respond to any hormones, because those same states had existed in the protein a relatively short time before," says Thornton.
这些受体将它们收到的信号传输给蛋白质组成的精密复合体,加工并储存信息。
These receptors feed the signals they receive to a delicate complex of protein-based machines that process and store the information.
贝尔的药物,称为STX107,可以抑制受体,削减与脆性X染色体相关联的蛋白质的生产过剩到一个正常的范围内。
Bear's drug, called STX107, inhibits the receptors to pare back the overproduction of proteins associated with Fragile X to a normal range.
这两种基因产生与上述受体结合的大量蛋白质,压制和削弱有功能肌肉生长抑制素分子的作用。
These churn out proteins which bind to the receptors, swamping and diluting the effect of functional myostatin molecules.
对成功的移植来说这些蛋白质应该在供体和受体之间相匹配。
For successful transplantation these proteins ideally should be matched between donor and recipient.
但他坚持认为这样的蛋白质数目可能会很多,因为在皮质醇受体的进化过程中,导致不可改变性的突变之间复杂的相互作用的形式比比皆是。
But he argues that the number is likely to be large because the type of complex interactions between mutations that caused irreversibility in the evolution of the cortisol receptor are common.
脆性X神经没有能力将从mGluR5受体收到的信息静音,从而导致生产过剩的蛋白质。
Fragile X neurons lack the ability to mute messages from the mGluR5 receptor, leading to an overproduction of protein.
这种蛋白质分子就是天然芳香烃受体(AHRs, arylhydrocarbonreceptors)。
Indeed, these proteins - aryl hydrocarbon receptors, or AHRs - are often referred to as dioxin receptors.
是否应该是 缺少关爱的老鼠糖皮质激素受体基因和 基因周边的蛋白质表现出高水平的甲基化及较低水平的乙酰化。 另,acetylation 是否应该是乙醇化?
Rats that had experienced little maternal care showed high levels of methylation and low levels of acetylation of the glucocorticoid-receptor gene and its neighbouring proteins.
十多年前就取得了重大进展,一个加州的生物科技公司Genentech(中文名:基因泰克)发行了一种药物,这种药物攻击蛋白质HER2(中文名:人表皮生长因子受体- 2)含量过多的乳腺癌细胞。
A breakthrough came more than a decade ago when Genentech, a Californian biotech firm, launched a drug that attacks breast-cancer cells with too much of a certain protein, HER2.
这种抗性并不是受体变化的结果,而是松鼠血清里蛋白质的作用,它们能抵消毒液的影响。
This resistance is not the result of altered receptors, but comes from the ability of proteins in their blood serum to neutralize the effects of venom.
该基因编码的一种蛋白质,也被称为趋化因子受体CXCR4,同样有助于艾滋病毒感染免疫细胞。
The gene codes for a protein, also called CXCR4, that also helps HIV infect immune cells.
当该蛋白质复合物正常发挥作用时,它使这些受体退回到神经细胞内-在此这些受体无法接受或响应有利突触生长的信号-在合适的时间内。
When the protein complex is working properly, it moves the receptors back inside the nerve cell - where they can no longer receive and respond to the pro-growth signal - at the appropriate time.
他们发现了一个称为多巴胺D2受体(DRD2)的分子的基因差异,DRD2受体是人脑细胞上对神经递质多巴胺敏感的一种蛋白质。
They found the differences in the gene for a molecule called the dopamine D2 receptor (DRD2), a protein present on brain cells that are sensitive to the neurotransmitter dopamine.
研究人员希望这项新技术广泛应用于受体和细胞膜蛋白质方面的研究并正在进行扩大应用范围研究。
The researchers are hopeful that this technology can be generalized across other receptors and cell-surface proteins, and are currently researching its broader applications.
这种蛋白质中在关键位置上含有苯基丙氨酸,它在与MC1R受体结合时起到很重要的作用。
These proteins have a phenylalanine in a key position that plays an essential role in binding on MC1R receptors.
蛋白偶联受体家族成员超过300种,它们构成了细胞膜中最大的蛋白质家族。
With more than 300 members, the G protein-coupled receptors constitute the largest family of proteins found in the membranes of cells.
首先阐述了分子对接设计的基本原理,然后在蛋白质受体中引入关键残基的概念,建立了一个新的柔性分子对接模型。
The basic theory of molecular docking design was first briefly described, and then the concept of the key residues in the protein receptor was introduced to establish a new flexible docking model.
新型IFN受体1结合蛋白质,编码它们的DNA,以及调节细胞对干扰素的反应的方法。
Novel IFN receptor 1 binding proteins, DNA encoding them, and methods of modulating cellular response to interferons.
新型IFN受体1结合蛋白质,编码它们的DNA,以及调节细胞对干扰素的反应的方法。
Novel IFN receptor 1 binding proteins, DNA encoding them, and method of modulating cellular response to interferons.
CCR5蛋白质主要覆盖于T细胞表面,是一种蛋白受体。
CCR5 protein coverage in the major T-cell surface, is a receptor protein.
它的目标是一种蛋白质:驱动肿瘤生长的表皮生长因子受体(EGFR)。
It targets a protein - epidermal growth factor receptor (EGFR) - which drives tumour growth.
激素不仅可能直接攻击晶状体蛋白质,而且也可能通过受体、细胞调控、黏附调节等间接发挥作用。
Glucocorticoids can bind lens protein directly or act through its receptor, cell regulation, adhesion regulation indirectly.
芯片大规模遥感实验的目的是最大限度地利用大众的样品可以用蛋白质芯片大光斑直径或多个景点每个受体每个基板。
Microarray mass-sensing assays aim to exploit maximally the analyte mass available by using a protein microarray with a large spot diameter or multiple spots of each receptor per substrate.
经过分类分析,下调基因,主要可以分为五个功能类:蛋白质降解、RNA转录调控、细胞壁合成降解、激酶受体和肽运输。
The down-regulated genes can be divided in five classes:protein degradation, RNA transcription, cell wall synthesis and degradation, kinase receptor and peptide transport.
本发明涉及用于杀伤携带促性腺激素释放素受体之肿瘤细胞的嵌合蛋白质。
The invention refers to the intrinsic protein used to kill the tumour cell taking short gland-hormone releasing-hormone receptor.
本发明涉及用于杀伤携带促性腺激素释放素受体之肿瘤细胞的嵌合蛋白质。
The invention refers to the intrinsic protein used to kill the tumour cell taking short gland-hormone releasing-hormone receptor.
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