目的:制备抗激活素受体相互作用蛋白1(ARIP1)抗体并探讨其应用。
Objective To prepare anti-activin receptor-interacting protein 1 (ARIP1) polyclonal antibody.
这表明钠离子通道阻断剂在与受体相互作用时具有共同的结构特征和作用方式,同时也为探讨受体结构提供了有价值的信息。
Studies of these results show that the sodium channel blockade has common structural features and way of action when interact with the receptor, thus leading to identical biological effect.
但他坚持认为这样的蛋白质数目可能会很多,因为在皮质醇受体的进化过程中,导致不可改变性的突变之间复杂的相互作用的形式比比皆是。
But he argues that the number is likely to be large because the type of complex interactions between mutations that caused irreversibility in the evolution of the cortisol receptor are common.
一旦更多了解受体、配体的相互作用以及从对靶子在溶液中的特性的高分辩率研究中获得更多的信息,人们就可以设计出更好的药物。
Better drugs will be designed once more is understood about receptor-ligand interactions and more information about targets is available from high-resolution studies of their properties in solution.
首先鉴定出的TRAF家族成员是TRAF1和TRAF2,发现它们能够与TNF受体2 (TNFRII)的胞质结构域相互作用(4)。
The first TRAFs identified, TRAF1 and TRAF2, were found by virtue of their interactions with the cytoplasmic domain of TNF-receptor 2 (TNFRII) (4).
它还可能与其它药物相互作用,特别是心血管一类药物,例如ace抑制剂、受体阻滞剂和保钾利尿剂。
It can also interact with other medications, especially certain types of cardiovascular medications such as ACE inhibitors, receptor blockers and potassium-sparing diuretics.
在过去十年中该受体被得到广泛研究,由于其重要性在于在正常和疾病状态调解细胞间和细胞与基质间的相互作用。
The past decade has seen an extensive investigation of this receptor owing to its importance in mediating cell-cell and cell-matrix interactions in both normal and disease states.
我们综述了RGD与整合素受体的相互作用,RGD生物活性的影响因素以及它在生物材料内皮化方面的应用。
In this review, the interaction of RGD peptides sequence and integrins, the influential factors of RGD peptides bioactivity and its application in endothelialization of biomaterials were discussed.
本文简要叙述了甜味剂理论,主要包括甜味剂的化学本质与呈甜味机理,甜味剂与甜受体的相互作用机理。
The paper briefly summarizes sweet agent theory, mainly consisting chemical essence, taste mechanism and the interaction mechanism between sweet and sweetener receptor.
G -蛋白偶联受体分布于细胞膜,与行使细胞通讯的分子(如神经递质和激素)发生相互作用。
Found in the cell membrane, GPCRs interact with molecules responsible for cellular communication such as neurotransmitters and hormones.
基底膜的组成成分通过和细胞表面受体整合素相互作用,在调节肿瘤转移的过程中发挥了重要作用。
The component of basement membrane plays important role in regulating tumor metastasis by interacting with cell surface receptor integrins.
层粘连蛋白是基底膜的重要成分之一,通过与其受体间的相互作用而具有广泛的生物学功能。
Laminin is an important component of basement membrane, it has extensive biological functions through the interaction with its receptors.
本文研究了在激发状态下芳烃(受体)和脂肪胺(给体)的相互作用以及高分子链在其中的影响。
The excited state interaction of some aromatic hydrocarbon (acceptor) -aliphatic amine (donor) systems and the effect of polymer chain have been studied.
白细胞介素2 (IL - 2)与其高亲和力受体(IL - 2r)的相互作用在调节T细胞免疫反应的强度和持续时间方面起着关键作用。
The magnitude and duration of T-cell immune response are critically regulated by the interaction of interleukin-2 (IL-2) and its high-affinity receptor (IL-2R) on the surface of the cell.
提示层粘连蛋白受体和配体的相互作用可影响胃癌的生长方式。
Suggesting that the interaction between the laminin receptor and its ligand may influence the mode of growth in GC.
还可能与其他药物相互作用,尤其是心血管药物,例如ace抑制剂,受体阻断剂和保钾利尿药。
It can also interact with other medications, especially certain types of cardiovascular medications such as ACE inhibitors, receptor blockers and potassium-sparing diuretics.
OPN通过与其主要的受体整合素和CD_(44)相互作用,参与多组织、多器官的生理病理过程。
Previous research found that OPN was involved in physiological and pathological processes in variety of tissues and organs through bindinging with integrins and CD_(44) receptors.
其方法的核心是对受体-配体相互作用的研究。
The kernel of the methodology focus on the studies of the interactions between receptor and ligand.
因此移植骨与受体的相互作用决定着骨移植的成败,最终要形成能够提供有效机械支撑的结构。
Thus, the interaction of the host and the bone graft determines the success of these procedures, which ultimately is to provide a mechanically efficient support structure.
研究中枢神经介素U(NMU)受体2(NMU2R)与黑皮质激素(MC)受体途径(MCR3/4)在调节摄食行为和能量平衡方面的相互作用关系。
This paper investigated the associations between central neuromedin U(NMU) receptor 2(NMU2R) and melanocortin(MC) receptor pathway(MCR3/4) in regulation of food intake and energy homeostasis.
结果该质粒有正确的阅读框,其表达蛋白不具有自主转录激活作用,与已知核受体辅活化子PNRC有明显的相互作用。
Results The protein expressed by the plasmid which had a correct reading frame, had no transcriptional activation and could interact with a known coactivator PNRC.
这表明细胞膜受体可能是电磁场与细胞相互作用的位点之一。
It suggested that receptor in the cytoplasmic membrane would be the site where low-frequency pulsed electrical field interacted with cells.
目的:探寻与G_CSF受体胞内区相互作用的下游蛋白因子,揭示G_CSF受体信号转导通路的可能机制。
Objective: to explore the protein factors that may interact with G_CSF receptor in the signal transduction pathways.
其方法的核心是对受体-配体相互作用的研究。
The kernel of the methodology focuses on the studies of the interactions between receptor and ligand.
生长调节剂对生物体的调控作用是通过调节剂与生物体细胞内的受体蛋白相互作用来实现的。
The regulation effect of growth regulator is realized by the interaction between receptive proteins in organism.
当谈到植物的天然免疫系统时,不能不提到相互作用的两个方面:植物细胞的受体分子以及与之成对的入侵细菌特异性的信号分子。
Rice growing. Scientists have identified the bacterial signaling molecule that matches up with a specific receptor in rice plants to ward off a devastating disease known as bacterial blight of rice.
这些结果说明,吡虫啉、杀虫双和乙酰胆碱受体发生相互作用过程存在差异。
This study shows that there is some pharmacological difference between Imidacloprid and Dimehypo during their interactions with the postsynaptic acetylcholine receptors.
其二,聚糖及其凝集素受体的相互作用在信号转导、抗原提呈、控制细胞发育与分化中起调控作用;
Secondly, interactions between glycans and lectins play key roles in signal transduction, antigen presenting, control of cell development and differentiation.
采用分子动力学和MM/PBSA相结合的方法预测了表皮生长因子受体和4-苯胺喹 啉类抑制剂的相互作用模式。
The possible binding mode between EGFR and a 4-anilinoqunazoline inhibitor was predicted by using molecular dynamics and MM/PBSA.
采用分子动力学和MM/PBSA相结合的方法预测了表皮生长因子受体和4-苯胺喹 啉类抑制剂的相互作用模式。
The possible binding mode between EGFR and a 4-anilinoqunazoline inhibitor was predicted by using molecular dynamics and MM/PBSA.
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