三组术前治疗均未发生严重不良反应，术中出血量、术中术后并发症发生率无显著性差异（P>0.05）。
There was no serious adverse reaction in the three groups; There was no significant difference in the blood loss, surgery complication of the three groups(P>0.05).
两组患者治疗期间均未见活动性出血、过敏等不良反应发生。
During the treatment, the two groups patients had no active bleeding, allergies and other adverse reactions.
安全性较高，临床有极少不良反应，未见严重出血事件。
There are high security, very few clinical adverse reactions, no serious bleeding events.
结论肾上腺皮质轴和甲状腺轴的异常应激反应性增强，是气温骤降促发高血压脑出血发病的重要机理之一。
Conclusion It is one of important mechanisms of the sudden drop of temperature inducing hypertensive cerebral hemorrhage that stress reactions of adrenal axis and thyroid axis are abnormally enhanced.
结论肾上腺皮质轴和甲状腺轴的异常应激反应性增强，是气温骤降促发高血压脑出血发病的重要机理之一。
Conclusion It is one of important mechanisms of the sudden drop of temperature inducing hypertensive cerebral hemorrhage that stress reactions of adrenal axis and thyroid axis are abnormally enhanced.
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