目的探讨细胞凋亡、促凋亡基因和凋亡抑制基因在吸入性损伤发生的作用及意义。
Objective To explore the role and significance of apoptosis, pro-apoptotic genes and apoptosis suppressor genes in the pathogenesis and development of inhalation injury.
癌基因，肿瘤抑制基因的发现促进了对细胞周期及细胞凋亡机制的深入理解。使人们对肿瘤发生和发展的认识也日趋深入。
The discovery of oncogene and tumor suppressor gene has deepened human beings understanding of the mechanisms of cell cycle and cell apoptosis as well as the mechanisms of tumorigenesis.
选择肿瘤细胞特异表达基因并特异性地抑制其表达，是靶向诱导肿瘤细胞凋亡的关键。
To induce tumor cell apoptosis effectively, we should select tumor cell- specific gene and inhibit its expression specifically.
目的探讨凋亡基因对大鼠心肌梗死的表达及血管紧张素转化酶抑制剂(acei)的干预作用。
Objective to investigate the expression of apoptosis - related genes in rats with myocardial infarction and effects of ACEI.
结果人LIF基因可在COS - 7细胞中进行有效表达，表达产物对HL - 60白血病细胞具有抑制生长和诱导凋亡的作用。
Results the LIF gene can express in COS-7 cells and the product exhibits following functions on HL-60 cells: inhibiting growth, inducing apoptosis.
BDNF基因修饰的大鼠淋巴细胞的培养上清可降低H2O2和DA对PC 12细胞生长的抑制率并能抑制H2O2和DA诱导PC 12细胞凋亡。
ResultsThe supernatant of lymphocytes modified by BDNF gene decreased the growth inhibitory rate and apoptosis rate of PC12 cells induced by H2O2 and DA.
结论：黄芪可抑制缺血区促凋亡基因的表达，增强抑凋亡基因的表达。
Conclusion:Astragalus could inhibit the expression of proapoptotic genes and enhance that of inhibiting-apototic genes in ischemia area after cerebral ischemia.
本研究发现SPATA4基因能够抑制细胞衰老和细胞凋亡、促进细胞周期的推进与细胞增殖；
This research reveals that SPATA4 gene can inhibit cellular senescence and apoptosis as well as promote the progression of cell cycle and cell proliferation;
中医药在抑制血管生成、促进细胞凋亡、调节内分泌系统和抑制癌基因表达方面对癌前病变的干预作用。
Traditional Chinese medicine (TCM) has shown effects on precancerous changes through inhibiting angiogenesis, promoting apoptosis, modulating endocrine system and restraining oncogene expression.
结论：向胃癌细胞中导入外源性FHIT基因可以抑制肿瘤细胞增殖，诱导细胞凋亡并引起细胞生长周期阻滞。
Conclusions: Transfecting the exogenous FHIT gene into gastric cancer cells can suppress the proliferation of tumor cells, and can also induce apoptosis and cell cycle arrest.
通过直接肌肉内注射进行基因转染，p X1具有诱导肝癌细胞凋亡、抑制肝癌生长的作用。
The transfection of plasmid pX1 by injection into muscle of mouse could produce the inhibitory effect on liver carcinoma growth by inducing cells…
运动训练可引起多种组织细胞的凋亡基因表达发生变化，这一变化可引起细胞发生凋亡和抑制凋亡的发生。
The sports training may cause changes of the apoptosis gene in many kinds of cell organizations, meanwhile this change may cause the cell producing apoptosis and inhibit this kind of apoptosis.
结果表明：①LMP1介导细胞凋亡和抑制细胞凋亡的基因的表达，同时上调或下调某些与细胞凋亡相关基因的表达；
The results showed that LMP1 up regulated the expression of some genes related to apoptosis and anti apoptosis, and down regulated the expression of some other genes of apoptosis and anti apoptosis;
抑癌蛋白p53通过调节下游靶基因的转录，参与细胞凋亡、细胞周期抑制、DNA损伤修复等多种生物学过程。
The tumor suppressor p53 regulates cell cycle arrest, apoptosis and DNA repair processes by controlling various target genes that contain p53 sequence-specific DNA binding sites.
抑癌蛋白p53通过调节下游靶基因的转录，参与细胞凋亡、细胞周期抑制、DNA损伤修复等多种生物学过程。
The tumor suppressor p53 regulates cell cycle arrest, apoptosis and DNA repair processes by controlling various target genes that contain p53 sequence-specific DNA binding sites.
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