结论全反式维甲酸对急性早幼粒细胞性白血病患者的预后有很大改善。
Conclusion There are significant improvement in prognosis of APL treated with ATRA.
结果在全反式维甲酸诱导前后的细胞之间存在明显的基因表达差异。
Results There were obvious differences in gene expression between human lung cancer cells before and after ATRA treatment.
目的探讨全反式维甲酸（ATRA）对糖尿病大鼠足细胞损伤的保护作用。
Objective To investigate the protective effect of all-trans retinoic acid (ATRA) on podocyte lesion in diabetic rats.
目的：克隆全反式维甲酸诱导前列腺癌细胞系DU 145细胞产生凋亡的相关基因。
Objective To clone the apoptosis-related genes induced by all trans-retinoic acid(ATRA) from prostatic carcinoma cell line DU-145, and investigate the molecular mechanism of the apoptotic process.
目的：探讨全反式维甲酸（ATRA）对人乳腺癌MCF-7细胞凋亡的影响及作用途径。
Objective To investigate the possible pathway of the effect of all-trans retinoic acid(ATRA) on the apoptosis of human breast cancer cell line(MCF-7).
本实验探讨全反式维甲酸和紫杉醇对S-D大鼠主动脉血管内皮细胞增殖的影响及其机制。
This study is designed to investigate the effect and mechanism of paclitaxel and all-trans retinoic acid on the growth of S-D rat aorta endothelial cells cultured on gelatin-coated dishes.
结论全反式维甲酸可以抑制睾丸卵黄囊瘤细胞的增殖，抑制肿瘤增殖机制可能与下调VEGF的表达有关。
ConclusionATRA could inhibit proliferation of yolk sac tumor cell line, and down regulation of VEGF could be the inhibitory mechanism of ATRA on yolk sac tumor cell line in vitro.
结论全反式维甲酸和康莱特注射液可逆转家兔颊黏膜鳞状上皮癌前病变，有可能成为新的化学阻断干预药物。
Conclusion ATRA and Kanglaite injection can reverse precancerous squamous epithelial lesions in rabbits and may be used as new intervention chemicals.
全反式维甲酸(atra)是一种用于肿瘤治疗的抗增殖药物，磁性纳米颗粒则是一种可用于肿瘤热疗的药物。
All-Trans Retinoic Acid (ATRA) is an antiproliferative drug against tumor and magnetic nanoparticles is a drug for tumor hyperthermia.
目的：探讨全反式维甲酸（tRA ）对大鼠棕色脂肪组织线粒体上解偶联蛋白（UCP）活性和含量的影响。
Objective: To evaluate effects of tRA on activity and content of UCP in rat brown adipose tissue mitochondria.
结论全反式维甲酸具有调控分化相关基因表达与否的重要作用，由RA诱导的肿瘤细胞再分化是一个多基因参与的过程。
Conclusion ATRA plays an important role in regulating the differentiation-related gene expression. ATRA-induced differentiation is a complex process with multiple genes involved.
结论全反式维甲酸治疗虽然影响APL患者血清tnf和IL - 6水平，但与该组患者的外周血wBC数量变化无线性关系。
Conclusion ATRA treatment can affect serum level of TNF or IL-6 in patients with APL, but neither TNF nor IL-6 has linear correlation with the variation of WBC number.
方法：应用全反式维甲酸诱导前列腺癌DU 145细胞凋亡，建立细胞凋亡模型，采用基于PCR的改良消减杂交技术克隆与凋亡相关的基因。
Methods Improved PCR-based subtractive hybridization was used to clone the genes from apoptotic prostatic carcinoma cell line DU-145 cells induced by ATRA.
方法：应用全反式维甲酸诱导前列腺癌DU 145细胞凋亡，建立细胞凋亡模型，采用基于PCR的改良消减杂交技术克隆与凋亡相关的基因。
Methods Improved PCR-based subtractive hybridization was used to clone the genes from apoptotic prostatic carcinoma cell line DU-145 cells induced by ATRA.
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