但动物模型研究显示B细胞在促进免疫耐受中可能也起作用。
Work in animal models indicates that B cells also may help promote immune tolerance.
免疫耐受疗法也被研究用于1型糖尿病的早期干预。
Immune tolerance therapies are also being investigated for use as early interventions for type 1 diabetes.
妊娠免疫耐受机理是生命科学和医学的研究热点之一。
The mechanism of pregnancy tolerance is a hot point of life science and medicine.
而HBV感染导致T细胞免疫耐受的确切机制还不清楚。
The mechanisms responsible for the T cell tolerance in chronic HBV infection are not completely understood.
越来越多的研究表明调节T细胞是外周免疫耐受的关键。
More recent researches have shown that regulatory t cell is a key element in peripheral tolerance.
目的探讨器官移植中间充质干细胞诱导免疫耐受的可能性。
Objective to investigate the possibility of immune tole rance induced by bone marrow-derived mesenchymal stem cells in allogeneic organ transplantation.
这对免疫耐受的病人如器官移植和接受化疗的病人尤其重要。
This is an extremely important consideration when dealing with immunocompromised patients such as organ transplant recipients or patients who are receiving chemotherapeutic agents.
结论新生猪同种异基因脐血输注能诱导受者对供者产生免疫耐受。
Conclusion Allogeneic umbilical blood infusion can induce immunological tolerance in the recipients in newborn pigs.
目的了解异基因骨髓注射在大鼠小肠移植中的免疫耐受作用和意义。
ObjectiveTo investigate the immune tolerance function and significance of allogene bone marrow injection to the small intestines transplantation of rats.
目的探索混合皮肤移植中,自体皮岛诱发移植免疫耐受的免疫机制。
Aim to explore the mechanism of the immune tolerance induced by the auto-islets in the intermingled skin grafting.
结论:胸腺移植对诱导免疫耐受、提高异种胰岛移植物存活有一定作用。
Concluson: Thymus transplantation is effective to induce xenograft tolerance and improve the functional survival time of islet xenograft.
但这些抗原多属自身抗原,普遍存在免疫原性低,易引起免疫耐受等缺陷。
But most of the antigen was the kind of self-antigen with the defects of poor-immunogenicity and easily-caused immunotolerance.
结论单一胸腺或腹腔内注射同种脾细胞可以诱导新生大鼠的特异性免疫耐受。
Conclusions Intrathymic or intraperitoneal inoculation of allogeneic cells in a neonatal recipient with an immature system can produce donor specific tolerance to a subsequent graft.
在免疫耐受网络系统的支持下,现在已经开展胰岛移植前瞻性多中心试验研究。
Islet cell transplantation now forms the basis of a prospective multicenter trial under the aegis of the Immune Tolerance Network.
关于免疫耐受的近期研究集中在一种称为调节性T细胞(Treg)的T细胞亚群的作用。
Recent studies of immune tolerance have focused on the role of a subset of t cells, called regulatory t cells (Tregs).
目的:探讨混合胸腺移植诱导移植免疫耐受而不发生自身免疫性疾病的可行性。
Objective:To explore feasibility of inducing immune tolerance and prevention of organ specific autoimmune disease by transplanting with mixed fetal syngeneic or allogeneic and xenogeneic thymus.
现阶段诱导免疫耐受的有效方法,主要有供者特异性输血和供者特异性骨髓移植。
At present the main effective strategies of inducing immune tolerance are donor specific blood transfusion and donor specific bone marrow transplantation.
阳性选择决定了成熟T细胞的MHC限制性,阴性选择使机体获得自身免疫耐受。
The MHC restriction of t cell is determined in positive selection. The tolerance of t cells to autoantigen is acquired during negative selection.
有效地控制慢性移植排斥反应和诱导移植免疫耐受是当今移植免疫学研究的热点。
The control of chronic transplant rejection and the induction of transplant graft tolerance today are the hottest research field in transplant immunology.
目的利用大鼠异位心脏移植模型,探讨门静脉注射供体脾细胞诱导免疫耐受的机制。
Objective on the rat model of heterotopic heart transplantation, the mechanism of immune tolerance induced by portal venous injection of donor spleen cells was studied.
目的探讨异基因小鼠髓腔内骨髓移植(IBM - BMT)诱导免疫耐受的效果。
Objective to explore the effect of allogeneic intra-bone marrow bone marrow transplantation (IBM-BMT) on the induction of immune tolerance.
因此,外来体可能具有细胞毒性效应、免疫调节、诱导凋亡和免疫耐受诱导等作用。
Exosomes, therefore, may be in possession of CTL effect, immune regulation, inducing apoptosis immune enduring and so on.
结论有些长期携带功能良好移植肾的患者已经获得对供者细胞特异的免疫耐受状态。
Conclusion Some of the patients carrying long - term and well - functioning renal grafts had become immunologic tolerant to donor cells.
结论胸腺内注射异基因MHC抗原可诱导大鼠对异体坐骨神经移植的特异性免疫耐受。
Conclusion Intrathymus injection of allogene MHC antigen might induce specific immune tolerance to sciatic nerve allografts in mice.
在产生免疫耐受的移植物中可发现调节性T淋巴细胞,并对移植组织具有保护性作用。
Regulatory T cells can be found in tolerated grafts and contribute to the acquisition of a state of privilege in those tissues.
结论桂枝汤可以增强痹证小鼠肠道黏膜免疫功能,从而可能诱导免疫耐受和免疫抑制。
ConclusionGZD could enhance the immune function in intestinal mucosa in mice with bi syndrome, thus it might induce immune tolerance and immune inhibition.
结论:同供体肾移植及骨髓细胞输注是一种可行的诱导免疫耐受的方法,且简便安全。
Conclusion: Donor bone marrow transfusion was safe and beneficial. It could induce specific immunologic tolerance in the renal allograft recipients.
目的:探讨眼前房内注射牛视网膜可溶性抗原(S抗原)在诱导眼免疫耐受中的作用。
Objective: to study the effect of injection bovine retinal soluble antigen (S-Ag) into anterior chamber (AC) in inducing immunological tolerance.
制备免疫耐受大鼠脾淋巴细胞培养上清,用夹心elisa法测定其中IL 10的水平。
The culture supernatants of splenic lymphocytes from oral immune tolerance rats were prepared. The IL-10 level in the supernatants was detected by sandwich ELISA.
制备免疫耐受大鼠脾淋巴细胞培养上清,用夹心elisa法测定其中IL 10的水平。
The culture supernatants of splenic lymphocytes from oral immune tolerance rats were prepared. The IL-10 level in the supernatants was detected by sandwich ELISA.
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