• 动物模型研究显示B细胞促进免疫耐受可能起作用。

    Work in animal models indicates that B cells also may help promote immune tolerance.

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  • 免疫耐受疗法研究用于1型糖尿病早期干预

    Immune tolerance therapies are also being investigated for use as early interventions for type 1 diabetes.

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  • 妊娠免疫耐受机理生命科学医学研究热点之一。

    The mechanism of pregnancy tolerance is a hot point of life science and medicine.

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  • HBV感染导致T细胞免疫耐受确切机制清楚

    The mechanisms responsible for the T cell tolerance in chronic HBV infection are not completely understood.

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  • 越来越多研究表明调节T细胞免疫耐受关键

    More recent researches have shown that regulatory t cell is a key element in peripheral tolerance.

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  • 目的探讨器官移植中间充质干细胞诱导免疫耐受可能性

    Objective to investigate the possibility of immune tole rance induced by bone marrow-derived mesenchymal stem cells in allogeneic organ transplantation.

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  • 免疫耐受病人器官移植接受化疗的病人尤其重要

    This is an extremely important consideration when dealing with immunocompromised patients such as organ transplant recipients or patients who are receiving chemotherapeutic agents.

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  • 结论新生猪同种异基因脐血输注诱导受者对供者产生免疫耐受

    Conclusion Allogeneic umbilical blood infusion can induce immunological tolerance in the recipients in newborn pigs.

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  • 目的了解异基因骨髓注射小肠移植中的免疫耐受作用意义

    ObjectiveTo investigate the immune tolerance function and significance of allogene bone marrow injection to the small intestines transplantation of rats.

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  • 目的探索混合皮肤移植,自体皮岛诱发移植免疫耐受免疫机制

    Aim to explore the mechanism of the immune tolerance induced by the auto-islets in the intermingled skin grafting.

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  • 结论胸腺移植诱导免疫耐受提高异种胰岛移植物存活有一定作用

    Concluson: Thymus transplantation is effective to induce xenograft tolerance and improve the functional survival time of islet xenograft.

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  • 这些抗原多自身抗原,普遍存在免疫原性低,易引起免疫耐受缺陷

    But most of the antigen was the kind of self-antigen with the defects of poor-immunogenicity and easily-caused immunotolerance.

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  • 结论单一胸腺腹腔内注射同种脾细胞可以诱导新生大鼠特异性免疫耐受

    Conclusions Intrathymic or intraperitoneal inoculation of allogeneic cells in a neonatal recipient with an immature system can produce donor specific tolerance to a subsequent graft.

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  • 免疫耐受网络系统支持现在已经开展胰岛移植前瞻性多中心试验研究

    Islet cell transplantation now forms the basis of a prospective multicenter trial under the aegis of the Immune Tolerance Network.

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  • 关于免疫耐受近期研究集中一种称为调节性T细胞(Treg)的T细胞亚群的作用。

    Recent studies of immune tolerance have focused on the role of a subset of t cells, called regulatory t cells (Tregs).

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  • 目的探讨混合胸腺移植诱导移植免疫耐受而不发生自身免疫疾病可行性

    Objective:To explore feasibility of inducing immune tolerance and prevention of organ specific autoimmune disease by transplanting with mixed fetal syngeneic or allogeneic and xenogeneic thymus.

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  • 现阶段诱导免疫耐受有效方法主要供者特异性输血供者特异性骨髓移植

    At present the main effective strategies of inducing immune tolerance are donor specific blood transfusion and donor specific bone marrow transplantation.

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  • 阳性选择决定了成熟T细胞的MHC限制性阴性选择使机体获得自身免疫耐受

    The MHC restriction of t cell is determined in positive selection. The tolerance of t cells to autoantigen is acquired during negative selection.

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  • 有效地控制慢性移植排斥反应诱导移植免疫耐受当今移植免疫研究热点

    The control of chronic transplant rejection and the induction of transplant graft tolerance today are the hottest research field in transplant immunology.

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  • 目的利用大鼠心脏移植模型探讨门静脉注射供体细胞诱导免疫耐受机制

    Objective on the rat model of heterotopic heart transplantation, the mechanism of immune tolerance induced by portal venous injection of donor spleen cells was studied.

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  • 目的探讨基因小鼠髓腔内骨髓移植(IBM - BMT)诱导免疫耐受效果

    Objective to explore the effect of allogeneic intra-bone marrow bone marrow transplantation (IBM-BMT) on the induction of immune tolerance.

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  • 因此外来体可能具有细胞毒性效应免疫调节诱导凋亡免疫耐受诱导等作用。

    Exosomes, therefore, may be in possession of CTL effect, immune regulation, inducing apoptosis immune enduring and so on.

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  • 结论有些长期携带功能良好移植患者已经获得供者细胞特异的免疫耐受状态。

    Conclusion Some of the patients carrying long - term and well - functioning renal grafts had become immunologic tolerant to donor cells.

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  • 结论胸腺内注射基因MHC抗原诱导异体坐骨神经移植特异性免疫耐受

    Conclusion Intrathymus injection of allogene MHC antigen might induce specific immune tolerance to sciatic nerve allografts in mice.

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  • 产生免疫耐受移植物发现调节性T淋巴细胞移植组织具有保护性作用。

    Regulatory T cells can be found in tolerated grafts and contribute to the acquisition of a state of privilege in those tissues.

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  • 结论桂枝可以增强小鼠肠道黏膜免疫功能从而可能诱导免疫耐受免疫抑制

    ConclusionGZD could enhance the immune function in intestinal mucosa in mice with bi syndrome, thus it might induce immune tolerance and immune inhibition.

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  • 结论:同供体移植骨髓细胞输注一种可行诱导免疫耐受的方法,且简便安全

    Conclusion: Donor bone marrow transfusion was safe and beneficial. It could induce specific immunologic tolerance in the renal allograft recipients.

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  • 目的探讨眼前房内注射视网膜可溶性抗原(S抗原)诱导眼免疫耐受中的作用

    Objective: to study the effect of injection bovine retinal soluble antigen (S-Ag) into anterior chamber (AC) in inducing immunological tolerance.

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  • 制备免疫耐受大鼠淋巴细胞培养上清,夹心elisa法测定其中IL 10水平

    The culture supernatants of splenic lymphocytes from oral immune tolerance rats were prepared. The IL-10 level in the supernatants was detected by sandwich ELISA.

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  • 制备免疫耐受大鼠淋巴细胞培养上清,夹心elisa法测定其中IL 10水平

    The culture supernatants of splenic lymphocytes from oral immune tolerance rats were prepared. The IL-10 level in the supernatants was detected by sandwich ELISA.

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