通过大量生物体dNA分子成像,光学标测可以相对廉价的绘制该生物体的基因组图。
By imaging large Numbers of an organism's DNA molecules, optical mapping can produce a map of its genome at a relatively low cost.
相比较而言,光学标测则可以测量基因组的绝对长度,并快速发现两个基因组之间的长度和结构差异。
Optical mapping, by contrast, can estimate the absolute length of a genome and quickly detect differences in length and structure between two genomes.
电压敏感染料的膜电位光学标测是一项集分子光子学、生理科学、计算机科学等诸多学科为一体的高科技技术手段。
Optical mapping of the membrane potential with voltage-sensitive dyes is an advanced approach that involves in many theories such as molecular photonics, physiology and computer science.
Green认为光学标测虽然“潜能巨大”,但要求有高水平的专家,以至于目前世界上只有几个实验室能使用该方法。
Though he called optical mapping "potentially very powerful, " Green added that it requires such a high level of expertise that only a couple of laboratories in the world use the method.
主要作者Anton Valouev(刚毕业于Waterman实验室,现在在斯坦福大学从事博士后工作)说,该法则使光学标测人类基因组成为可能。
Lead author Anton Valouev, a recent graduate of Waterman's lab and now a postdoctoral fellow at Stanford University, said the algorithm makes it possible to optically map the human genome.
主要作者Anton Valouev(刚毕业于Waterman实验室,现在在斯坦福大学从事博士后工作)说,该法则使光学标测人类基因组成为可能。
Lead author Anton Valouev, a recent graduate of Waterman's lab and now a postdoctoral fellow at Stanford University, said the algorithm makes it possible to optically map the human genome.
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