方法:以HPV16E749 - 57及其修饰肽免疫荷瘤小鼠,研究小鼠肿瘤的生长特性和转移规律。
Methods: the mouse with tumor was immunized with HPV16E749-57 and the peptide modified from E749-57, and growth behavior and metastatic pattern of tumor were studied in mouse.
着重总结了非蛋白氨基酸对生物活性肽进行修饰的方式和构效关系研究的进展。
Recent progress in modifying the bioactive peptides with non - protein amino acids and their preferences are generally reviewed.
李的新方法,与此相反,可以让研究人员构建一个单一的简单的“骨架”肽,加入简单试剂后它可被修饰成其他任何需要的肽。
Li's new process, by contrast, allows researchers to construct a single, simple "skeleton" peptide which can be modified into any other peptide needed with the addition of a simple reagent.
结论:本法适应于天花粉蛋白药物的肽谱分析,同时也为分析PEG修饰天花粉蛋白药物肽图谱提供了可以借鉴定手段。
Conclusion: the method is suitable for the peptide mapping of TCS, and it also provides a selective analysis method for TCS protein drug by PEG modification.
描述了修饰的信号肽,包括来自免疫球蛋白轻链的那些。
Modified signal peptides, including such from immunoglobulin light chains, are described.
尽管研究者已在原核细胞表达系统对胸腺肽的表达进行了研究,但由于原核表达系统缺乏翻译后的加工修饰等缺点,限制了其应用。
Although the thymosin has been successfully expressed in the prokaryotic cell system, its application is restricted because of its deficiency of modification after translation.
针对抗原多肽的结构特点,该团队通过人工修饰合成了抗原变构肽。
Against the peptide antigen structure of the team through artificial modification of the antigen peptide conformation change.
针对抗原多肽的结构特点,该团队通过人工修饰合成了抗原变构肽。
Against the peptide antigen structure of the team through artificial modification of the antigen peptide conformation change.
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