目的筛选与苯中毒有关的DNA复制及损伤修复基因。
Objective To screen DNA replication, and damage repair genes associated with benzene poisoning by using gene expression profile analysis.
研究DNA修复基因XRCC1多态性与辐射损伤易感性的关系。
To explore the relationship between polymorphisms of DNA repair gene XRCC1 and susceptibility to radiation injury.
结果表明，酒精(乙醇)转换成乙醛后破坏dna，激活细胞内dna的修复基因。
The results confirmed that the alcohol (ethanol) was being converted to acetaldehyde, causing DNA damage and switching on the cell's DNA repair genes.
综述了一些癌基因、肿瘤抑制基因和DNA修复基因对细胞电离辐射敏感性的影响。
Reported effects of some oncogenes, tumour suppressor genes and DNA repair genes on sensitivity of cells to ionizing radiation are reviewed.
由于错配修复基因缺陷而导致的基因组不稳定，被认为是导致肿瘤发生的一条新途径。
The instability of genome which results from defect of MMR genes is thought as a new oncogenesis way.
背景与目的：研究碱基切除修复基因XRCC1基因G28152A单核苷酸多态与肺癌风险的关系。
BACKGROUND&AIM: To evaluate the correlation between the single nucleotide polymorphism of XRCC1gene G28152A and the risk of lung cancer.
目的了解错配修复基因MSH6在不同形式大肠癌人群中的种系突变频率及特征，提供真正的突变热点。
Objective To explore germline mutation frequencies and features of mismatch repaired gene MSH6 in persons with different kinds of colorectal cancer.
目的：探讨核苷酸切除修复基因ERCC1在肺癌中的表达及其与多环芳烃(PAH) -DNA加合物的关系。
AIM: To investigate the expression of nucleotide excision repair gene ERCC1 and its relationship with PAH (polycyclic aromatic hydrocarbons) -dna adducts in lung cancer tissues.
目的运用低密度表达谱芯片检测人脑原发胶质瘤组织中DNA损伤修复基因的表达情况，进一步分析其表达变化的意义。
Objectives to detect the expression of DNA repair genes in primary glioma tissues by low-density array, and to analyze the significance of the expression.
目的探讨DNA修复基因XRCC1、XRCC3多态性与慢性苯中毒遗传易感性的关联及其与慢性苯中毒潜伏期的关系。
Objective To explore the association between genetic polymorphisms of DNA repair genes XRCC1 , XRCC3 and susceptibility to chronic benzene poisoning.
目的探讨晚期非小细胞肺癌(NSCLC)组织中DNA修复基因家族成员ERCC1、RRM1和BRCA1的表达及其临床意义。
Objective To investigate the expression of DNA repair gene family members of ERCC1, RRM1 and BRCA1 in tissues of advanced non-small cell lung cancer (NSCLC), and explore its clinical significance.
结论苯中毒患者外周血白细胞的DNA复制及损伤修复基因与正常人相比存在差异性表达，为进一步筛选苯中毒生物标志物提供了依据。
Conclusions Some DNA replication, and damage repair genes associated with benzene poisoning show differential expression, which provides the basis for screening biomarkers of benzene poisoning.
之后，这些小的反义RNA可能会在RNA拼接中发挥作用，如在选择压力下修复基因组中一个区域，抑或在丧失或损坏一个模块后恢复一个读码框。
Such small antisense RNAs may later have gained a role in RNA editing, possibly under selective pressure to repair a region or restore a reading frame after loss or erosion of a module.
砷可能通过抑制砷中毒患者皮肤组织中MGMT、XRCC1等DNA修复基因的表达，影响基因组d NA稳定性和DNA修复功能而导致对皮肤的致癌作用。
Arsenic causes carcinogenicity on human skin through inhibiting the expressions of MGMT, XRCC1 and influencing the genetic stability and the DNA repair function.
这些属性是正常细胞的基因编程功能，此举的目的是抗击感染或修复损伤。
These attributes are genetically programmed functions of normal cells that are intended to combat infection or repair injury.
我们正在向能够做到常规修复，从人体移除或甚至是注入基因的时代前进。
We're moving toward a time when we can routinely repair, remove or even insert genes in people.
可能是修复氧化了的基因材料的细胞工具，或者是中和自由基的分子——由机体自身产生或通过饮食摄入。
These can be cellular tools that repair oxidised genetic material, or molecules that are either manufactured by the body itself or consumed through the diet, which neutralise free radicals.
为了找出原因，研究员分析了那种基因在获得耐药性是转录的最多，辨别几种参与了DNA修复途径。
To figure out why, the researchers analyzed which genes were being transcribed more as resistance developed, and identified several that are involved in DNA repair pathways.
不过现在有一种新技术，通过一种特殊的基因修复这些受损的肺脏，使得这些肺脏能够应用于器官移植。这一技术的详细信息刊载于这周出版的《科学—转化医学》杂志上。
But a new approach, detailed this week in the new journal Science Translational Medicine, describes a novel gene therapy that can repair these damaged lungs-and make them available for transplant.
研究中收集到的其他基因则承担着更精细的修复工作，比如修复dna的小伤口和错误。
Other genes in the collection have more-precise repair duties, fixing small nicks and mistakes in DNA.
基因变异的虫子向我们演示，自由基可以帮助触发身体的保护和修复机制。
The genetically modified worms demonstrated that the production of free radicals can help to trigger the body’s general protective and repair mechanisms.
甚至相同种类的基因突变也已表现出生态系统如何悬崖勒马并自我修复。
Even genetic variation within the same species has been shown to affect how well ecosystems pull up their socks and repair themselves.
被BRCA1基因编码的蛋白质与DNA修复有关。
基因对端粒酶水平是起了一定作用，但这个实验所观察的并非基因的问题，这完全是身体以外的因素对身体带来的影响，其影响的结果就是端粒的自我修复水平。
Genes play a role in telomerase levels, but this was not genes. This was something impacting the body that came from the outside and affecting its ability to repair itself.
这种EphA2基因能够编译一种酶，这种酶对眼睛里受损蛋白质的修复发挥作用。
The EphA2 gene encodes an enzyme that plays a role in the repair of damaged proteins in the eye.
在通常情况下，像人类一样携带相同p 53基因的斑马鱼可以承受小剂量的放射，放射会对DNA造成损坏，而基因会加入对损坏的修复。
Normally zebrafish, which carry the same p53 gene as humans, can survive low doses of radiation, which causes damage to the DNA, because the gene steps in to repair that damage.
刊登在《自然》杂志上的这项研究特别标出了一个常见的基因变异。如果能将其修复，孤独症病例可能会减少15%。
The Nature study highlighted one common genetic variant which, if corrected would cut cases of autism by 15%.
这段DNA位于3号染色体上，与基因terc相邻。基因terc可以制造出一种酶，能在端粒缩短时对端粒进行修复。
The section of DNA was found on chromosome three, next to a gene called TERC, which makes an enzyme that repairs telomeres when they shorten.
这段DNA位于3号染色体上，与基因terc相邻。基因terc可以制造出一种酶，能在端粒缩短时对端粒进行修复。
The section of DNA was found on chromosome three, next to a gene called TERC, which makes an enzyme that repairs telomeres when they shorten.
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