这两种感染都是严重威胁生命的疾病,尤其对于免疫功能抑制的患者,侵袭性真菌疾病所致的死亡率常超过30%。
Infection with either can lead to severe life-threatening disease, particularly in immunosuppressed patients, with mortality rates for invasive fungal disease often exceeding 30%.
随着免疫抑制剂、广谱抗菌素、器官移植和侵袭性操作应用的增加,侵袭性真菌病的发生率也相应地增加。
With increasing application of immunosuppressor, broad-spectrum antibiotics, organ transplantation and invasive manipulation, the incidence of invasive fungal disease is rising.
侵袭性真菌感染,尤其是念珠菌血症和系统性念珠菌病,在过去几十年已成为发病率和死亡率的主要原因。
Invasive fungal infections, especially candidemia and systemic candidiasis, have become a major cause of morbidity and mortality in the last few decades.
在HPV检测组较低的死亡率是由于降低了晚期病变的筛出率,而且由于对更多的癌前病变的早期发现和治疗从而更有效的阻止了侵袭性癌的发生。
The lower death rate in the HPV-testing group is due to lower advanced disease and higher prevented invasive cancers due to early detection and treatment of more 'real' precursor lesions.
用目视检测得到的活动性头虱侵袭的患病率比真实的被低估了3.5个因子。
The true prevalence of active infestation was underestimated by visual inspection by a factor of 3.5.
胃癌死亡率居高不下的原因主要在于广泛的侵袭和转移。
The reason that it causes the high death rate lies in the wide invasion and metastasis.
这种癌前病变的早期观察和治疗使得晚期癌症发生率降低,而且在HPV检测组的侵袭性癌和宫颈癌死亡数都明显减少。
The early detection and treatment of such lesions resulted in a lower rate of advanced cancers, and a lower number of invasive cancers and cervical cancer deaths in the HPV-testing group.
新的抗真菌药物、免疫调节疗法和多种联合治疗方案的出现,使得侵袭性曲霉病患者的存活率有了显著提升。
With the emergence of new antifungal agents, immunomodulation intervention and combination therapy, the survival rate of patients with invasive aspergillosis has been improved greatly.
背景侵袭和转移是恶性肿瘤的重要特征,是影响肿瘤治愈率的主要因素。
BackgroundInvasion and metastasis are important characters of malignant tumors and main obstacles to the cure rate of tumors.
结论成功构建稳定沉默CXCR4表达的肾癌a 498细胞株,转染后的细胞凋亡率升高,体外侵袭能力降低,为后续研究奠定了基础。
ConclusionWe have successfully established an A498 cell line with CXCR4 stably silenced; the cell line has a higher apoptotic rate and lower invasion ability, which paves a way for future research.
肺癌作为我国发病率、死亡率增长最快,对人类健康和生命威胁最大,预后最差的肿瘤之一,侵袭转移是导致其治疗失败和死亡的主要原因。
Lung cancer with poorest prognosis is the largest threaten to people's health and life. The incidence and mortality of it is increasing most fast in our country.
本法操作简单、安全、侵袭小、病人痛苦少、阳性检出率高。
This method has such advantages as simple and easy operation, safety and high detection rate.
我们已经饱受如艾滋病,肺结核及疟疾这样的全球性疫情的侵袭。而流感疫情与其他病所不同的是,它很容易传染。在美国,季节性流感是死亡率最高的十种病之一;
That deaths from the new virus have mostly been confined to Mexico is probably a consequence of its having appeared there first and spread, under cover of normal seasonal flu, without anyone noticing.
结果:本组侵袭性垂体瘤全切除和次全切除率为80%,无手术死亡,无严重手术并发症。
Results: Total and subtotal resection rate was 80% and no surgical died case and occurrence of severe complication.
这一高分辨率的三维结构阐明了这一分子怎样发挥功能并能够精确控制其活动,它具有控制人类免疫缺陷病毒感染和阻止癌症侵袭扩散的潜力。
The high-resolution structure sheds light on how the molecule functions and could point to ways to control its activity, potentially locking out HIV and stalling cancer's spread.
目的侵袭性曲霉菌病(IA)在血液病患者发病逐年增多,且伴随很高的病死率。
Objective The incidence of invasive aspergillosis (IA) is increasing in patients with hematological disorders and it may lead to a high mortality rate.
防止肿瘤发生、进展和侵袭转移是降低膀胱癌复发率和病死率的关键。
To prevent the tumorigenesis, progression, invasion and metastasis is the key point to decrease the recurrence rate and case fatality rate.
粘液分泌功能分化型(MSFDT):54例,占全组的15%,以局部垂直向胃壁深层侵袭为主,手术时绝大多数(98.1%,53/54)已侵透浆膜,术后5年生存率为28.6%。
Mucin secreting function differentiation type(MSFDT): 15% of the series; 98.1%(53/54) of cases of this type had the serosa involved at operation; the 5-year survival rate was 28.6%.
肝细胞肝癌具有起病隐匿,恶性程度高,侵袭性生长快速,治疗后易复发,病死率高等特点。
Hepatocellular carcinoma is also a high malignancy with insidious onset, invasive fast-growing, high recurrence rate and fatality.
虽然各种诊治措施不断进展,但是甲状腺癌的远期生存率仍然没有得到明显的提高,肿瘤细胞的侵袭和远处转移是其治疗失败的主要原因。
Despite recent advancements in diagnosis and treatment, the long-term survival rate has undergone little improvement in the recent years, which is attributed mainly to tumor invasion and metastasis.
FHIT基因的改变与肝癌的演进、侵袭性、复发率和生存率等多项临床病理指标有关。
The alternations of FHIT gene correlate with several clinic pathological indicators such as progression, invasion, relapse rate, and survival rate of liver cancer.
近年来,侵袭性曲霉病发病率不断上升,并成为免疫抑制患者死亡的主要原因之一。
Recently, the incidence of invasive Aspergillosis is on the rise and it has become one of the major death causes in patients with immune function suppression .
近年来,侵袭性曲霉病发病率不断上升,并成为免疫抑制患者死亡的主要原因之一。
Recently, the incidence of invasive Aspergillosis is on the rise and it has become one of the major death causes in patients with immune function suppression .
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