目的探讨乳腺癌组织中DNA依赖蛋白激酶（DNA-PK）的表达变化及其意义。
Objective To investigate the expression change of DNA-PK in breast cancer tissue and the clinical significance.
对有肺癌的实验鼠进行实验，研究发现依赖性蛋白激酶1 (Cdk1)让DNA停止修复。
In experiments on mice with lung tumours the researchers showed that blocking a molecule called Cdk1 also stopped DNA repair.
特异的信号基序不仅包括蛋白激酶可以识别的序列(1)，也包括那些能够被磷酸化依赖结合蛋白如14-3-3识别的序列(2)。
Specific signaling motifs include not only sequences that are recognized by protein kinases (1), but also those that are recognized by phosphorylation-dependent binding proteins such as 14-3-3 (2).
目的研究DNA依赖性蛋白激酶(DNA- PK)活性和脑胶质瘤化疗敏感性的关系。
Objective To investigate the relationship between DNA-dependent protein kinase (DNA-PK) activity and anti-cancer drug sensitivity in human glioma tissues.
主要观察指标：神经细丝的磷酸化程度及糖原合酶激酶3、细胞周期依赖性蛋白激酶5的酶活性。
MAIN OUTCOME MEASURES: The degree of NF phosphorylation and the activities of GSK-3 and CDK-5 were mainly observed.
主要观察指标：神经细丝的磷酸化程度及糖原合酶激酶3、细胞周期依赖性蛋白激酶5的酶活性。
MAIN OUTCOME MEASURES: The degree of NF phosphorylation and the activities of GSK-3 and CDK-5 were mainly observed.
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