通过磷酰氯与手性仲胺的亲核取代反应高产率地合成了手性HMPA 类似物。
The chiral HMPA analogues were prepared in high yield by nucleophilic substitution between the chiral secondary amine and phosphoryl chloride.
胺能参加与卤代烷的亲核取代反应。
Amines can engage in nucleophile substitution reaction with alky.
提出自由基ips O亲核取代反应机理。
涉及36的这种逐步亲核取代是不大可能的。
A stepwise nucleophilic displacement involving 36 was highly unlikely.
氨基- 1,2,4 -三唑与苦基氯的亲核取代反应动力学研究。
Kinetics of the Nucleophilic Substitution of 3-amino-1, 2, 4-triazole with Picryl Chloride.
方法：通过亲核取代、还原、氧化、亲核加成等反应得到目的化合物。
METHODS: Electrophilic substitution, reduction, oxidation and nucleophilic addition reaction were used in the synthesis of title compounds.
季铵化反应是一类重要的SN2亲核取代反应，溶剂对该反应的影响很显著。
Quaternarization is an important SN2 nucleophilic substitution reaction; solvent has remarkable effect on it.
以磷酰氯为原料通过与手性仲胺的亲核取代反应高产率地合成了手性HMPA类似物。
The chiral HMPA analogues 1 and 2 were prepared in high yield by nucleophilic substitution between the chiral secondary amine and phosphoryl chloride.
将母体染料的中位氯原子用氨基试剂亲核取代，衍生合成了五个中位仲胺七甲川菁染料。
Five derivative dyes from the parent dyes were obtained by similar nucleophilic substitution reaction in which five primary amines were employed as the nucleophilic reagent.
氢的替代亲核取代反应(VNS)是与硝基芳环的亲电反应、亲核反应不同的一种新反应。
Vicarious nucleophilic substitution (VNS) of hydrogen is a new type of reaction which is different from the usual electrophilic and nucleophilic reactions of the nitro arenes.
它与环氧树脂混合后首先形成过渡状态，然后按双分子亲核取代(SN2)机理进行开环反应。
After it was mixed with epoxy resin, transition state was formed first. Then they got on with opening ring reactions according to bimolecular nucleophilic substitution mechanism (SN2).
考察了微波技术、反应物料比、催化剂以及溶剂等主要条件对亲核取代反应和产物收率的影响。
The effect of process conditions, such as microwave, reactant ratio, catalyst and solvent etc, on the nucleophilic substitution and yield of product were investigated.
以乙醇胺为起始原料，经亲核取代、肖特一鲍曼反应和缩合反应制得吗氯贝胺，总收率可达71.2%。
Moclobelide was synthesized from ethanolamine by nucleophilic substitution and Schotten-Baumann reaction, followed by condensation with an overall yield of 71.2%.
在我们的合成方法中，先从-苯乙醇开始合成了-苯乙基氯，再用丙二酸二乙酯的烯醇盐离子进行亲核取代。
First we synthesized the -phenylethyl chloride from -phenylethyl alcohol. Then it was substituted by enolate anion of diethyl malonate and converted to ester.
前言：结合双分子亲核取代反应机理，对乙醇和盐酸反应过程进行分析，合理确定了工业生产乙基氯的工艺路线。
Combine with the"S N2 "mechanism, after analyses the reaction process of alcohol and hydrochloric acid, we reasonably determined the industrial process for the production of Ethyl chloride.
两条路线中关键的一步反应是芳胺和溴代化合物的亲核取代反应，一般这步反应产率很低，并且需要较长的反应时间。
The key step of the two routes is the reaction of nucleophilic substitution of aromatic amines and -bromo compounds. Generally the produce rate of this reaction is low and the reaction time is long.
以2,3 -二氯苯胺为原料，经3步亲核取代反应合成了阿立哌唑。3步反应的收率分别为83%，91%和90%；总收率68%。
Aripiprazole in overall yield of 68% was synthesized from 2, 3-dichloroaniline by a three-step nucleophilic substitution reaction in yield of 83%, 91% and 90%, respectively.
并且对亲核试剂的体积效应、溶剂效应对亲核性影响，底物上吸电子基团的数目、吸电子能力对亲电性的影响，以及亲核取代反应的发生部位受哪些因素影响进行探讨。
At the same time, discuss about the impact factor to nucleophilicity such as the number of attract electron group, ability of attract electron and the nucleophilic substitution reaction part.
亲核性芳香取代。多取代苯衍生物合成的策略。
Nucleophilic Aromatic Substitution. Strategies in the Synthesis of Multisubstituted Benzene Derivatives.
亲核性芳香取代。多取代苯衍生物合成的策略。
Nucleophilic Aromatic Substitution. Strategies in the Synthesis of Multisubstituted Benzene Derivatives.
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