这才是真实的二甲胺四环素。
因为二甲胺四环素攻击的是细胞而不是病毒蛋白。
Because minocycline attack the cell rather than viral proteins.
但遗憾的是二甲胺四环素人仍不能完全去除病毒。
It is regrettable that minocycline are still not completely remove the virus.
二甲胺四环素只攻击那些受感染的T细胞，所以针对性极强。
Minocycline only attack those who are infected T-cells, therefore, extremely targeted.
目的：评价盐酸二甲胺四环素牙周缓释剂对慢性牙周炎的临床疗效。
Objective:to evaluate the diagnostic value of Periocheck chair-side examination and clinical effect of local application of minocycline ointment in the treatment chronic periodontitis.
目的：研究盐酸二甲胺四环素牙科软膏缓释剂治疗牙周炎的临床疗效。
Objective:to study clinical effects of minocycline hydrochloride ointment in treatment of periodontitis.
虽然HAART降低活跃的复制很有效，二甲胺四环素是对抗病毒的另一重要手段。
While HAART is really effective in keeping down active replication, minocycline is another arm of defense against the virus.
试验证明，二甲胺四环素可极大地降低病毒量，而且影响T细胞的活化与繁殖。
Experiment proved that minocycline could greatly reduce the virus load, but also affects T-cell activation and reproduction.
队伍使用分子标志物发现二甲胺四环素非常选择性的阻断T细胞激活的特定专门的信息传导途径。
The team used molecular markers to discover that minocycline very selectively interrupts certain specific signaling pathways critical for T cell activation.
“二甲胺四环素降低了病毒脱离休眠状态的感染T细胞的能力，”Szeto解释说。
"Minocycline reduces the capability of the virus to emerge from resting infected t cells," Szeto explains.
文章的作者总结道，二甲胺四环素的神经保护和抗炎作用很可能是由于抑制了PARP-1。
The study authors conclude that it is very likely that minocycline's neuroprotective and anti-inflammatory effects are due to PARP-1 inhibition.
结果：二甲胺四环素在体外具有刺激骨髓基质细胞和成骨细胞增殖的作用，但抑制细胞的分化。
Result: minocycline can stimulate the proliferation of osteoblast and marrow stromal cell, but also can restrain the differentiation.
在给予二甲胺四环素的猴子中，病毒装载进入脑脊液，病毒RNA在脑部以及中枢神经系统疾病的严重性降低。
In monkeys treated with minocycline, the virus load in the cerebrospinal fluid, the viral RNA in the brain and the severity of central nervous system disease were significantly decreased.
动物实验的成功促使研究小组进行试管研究，以确定二甲胺四环素疗法能否影响感染HIV的人类T细胞的潜伏病毒。
The success with the animal model prompted the team to study in test tubes whether minocycline treatment affected latency in human t cells infected with HIV.
Kauppinen发现二甲胺四环素是一种从四环素分离得到的抗生素，它能阻止培养细胞的炎症反应和凋亡。
Kauppinen found that minocycline, an antibiotic derived from tetracycline, prevents inflammation and apoptosis in cultured brain cells.
直到现在二甲胺四环素药物的作用机制仍不是十分清楚，SFVAMC神经康复学主要研究员Raymond A。
The way in which minocycline works has been very unclear until now, says principal investigator Raymond A. Swanson, MD, chief of neurology and rehabilitation at SFVAMC.
虽然不能完全消除病毒，但二甲胺四环素为科学家们指明了一条方向，即寻找更多作用等同于二甲胺四环素的药剂。
Although we can not completely eliminate the virus, but minocycline for scientists pointed out a direction, that is equivalent to looking for more role of the pharmaceutical minocycline.
克莱·门特斯表示，二甲胺四环素能够降低T细胞的激活和增殖能力，这是从HIV感染者变成艾滋病患者所要经历的两个重要步骤。
According to Clements, minocycline reduces the ability of t cells to activate and proliferate, both steps crucial to HIV production and progression toward full blown AIDS.
科学家们发现，二甲胺四环素配合鸡尾酒疗法(HAART)有望改善传统治疗艾滋病的方法，而且可降低病毒的耐药性。
Scientists have found that minocycline with the cocktail therapy (HAART) is expected to improve the traditional method of treatment of AIDS, but also can reduce the virus resistance.
Swanson博士说：“二甲胺四环素是一种极其有效的PARP抑制剂，比市场上标明PARP抑制剂的药物更有用。”
"Minocycline turns out to be an extraordinarily good PARP inhibitor, better than most of the drugs that are marketed as PARP inhibitors," he says.
HAART以病毒本身为靶子，与这种疗法使用的药物有所不同的是，二甲胺四环素采取的是导向目标追踪方式，调节免疫系统的主要行动者以及HIV感染目标T细胞。
Unlike the drugs used in HAART which target the virus, minocycline homes in on, and adjusts t cells, major immune system agents and targets of HIV infection.
HAART以病毒本身为靶子，与这种疗法使用的药物有所不同的是，二甲胺四环素采取的是导向目标追踪方式，调节免疫系统的主要行动者以及HIV感染目标T细胞。
Unlike the drugs used in HAART which target the virus, minocycline homes in on, and adjusts t cells, major immune system agents and targets of HIV infection.
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