方法：检索并分析釉原蛋白基因的上游调控序列。
METHODS: The upstream regulation sequences of amelogenin gene were retrieved and analyzed.
目的探讨白念珠菌耐药基因CDR1基因上游调控序列对氟康唑耐药的影响。
Objective To appraise the relationship between fluconazole resistance and expression of the CDR1 gene upstream regulation sequence.
因此选择对基因的表达具有重要功能的外显子1和其上游的调控区及下游外显子内含子交界区序列通过直接测序法进行SNP筛查，并进一步分析多态位点与病窦的关联性。
Therefore the other aim of our study is to discover SNPs of HCN4 exon 1, including the regulatory sequence and exon-intron boundary of it, which plays an importable role of channel function.
因此选择对基因的表达具有重要功能的外显子1和其上游的调控区及下游外显子内含子交界区序列通过直接测序法进行SNP筛查，并进一步分析多态位点与病窦的关联性。
Therefore the other aim of our study is to discover SNPs of HCN4 exon 1, including the regulatory sequence and exon-intron boundary of it, which plays an importable role of channel function.
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