Smith first worked with Boyle on the soundtrack for the Oscar-winning director's earlier film Trainspotting.
The drama will also star Trainspotting actor Peter Mullan and Lord of the Rings star David Wenham.
The Scottish Drugs Forum director said the move could help the "Trainspotting generation" of problem drug users.
Boyle is collaborating with electronic musical duo Underworld, whose 1990s rave classic Born Slippy featured in Trainspotting.
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If Weinstein wants to deal with difficult subjects and is planning to mine his greatest hits further, how about a Trainspotting musical?
The Trainspotting actor sang live for his part as Kurt Wild, but he wasn't afraid of showing off his musical skills during filming.
The cold turkey scene has cropped up in films like Trainspotting and soap operas like EastEnders, where a parent uses so-called "tough love".
FilmFour produced many of Britain's most successful films over the last 20 years, from Trainspotting and the Crying Game to Four Weddings and a Funeral.
Still, it would take some serious trainspotting to tell the difference.
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But if their protagonists are polar opposites, both stories -- one as told in Aravind Adiga's best-selling novel "The White Tiger, " the other in "Slumdog Millionaire, " the new movie from "Trainspotting" director Danny Boyle -- have much in common.
Danny Boyle, the Oscar-winning director -- and east London resident -- best known for hit movies " Trainspotting" and " Slumdog Millionaire" was the man responsible for the Olympic opening ceremony, the show that televisions around the world were tuned in to at the start of London's long-awaited Games.
Entitled "Isle of Wonder, " Boyle -- the Oscar-winning director best known for hit movies "Trainspotting" and "Slumdog Millionaire" -- put together a star-studded on-field dramatization that drew on Shakespeare and Brit Pop to chart Britain from its pastoral roots through the Industrial Revolution to James Bond, Harry Potter and the Beatles.
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