Murray's spirited Serbian opponent battled back from a break down to take the first set to a tie break.
On gun control: When Bradley reached into the history books and chastised his opponent for voting against several gun control measures as a congressman, Gore proudly reminded the audience that, as vice president, he had voted to break a Senate tie and enact the ban on assault weapons.
The 26-year-old Clijsters battled back to tie it up at 3-3, and then both players squandered potentially match-winning break opportunities to ensure a tie-break.
There was never any sign of a break in the third either and it was no shock when it too went to a tie-break which Murray won 7-4 to set up a clash with Radek Stepanek in the third round.
Navarro hit a solo homer just over the basket at the wall in left-center in the second to break a 1-all tie and added a two-run shot down the left-field line off John Danks (0-1) in the fourth, with both drives coming from the right side.
Soderling, who had won six of their previous nine meetings, failed to convert two break points of his own in the next game and the set went to a tie-break.
Parmar then thumped down two aces to take the set to a tie-break.
The Serb looked comfortable and made it 4-4 to take the set to a tie-break, which the world number four won.
After losing the first set, Jackson and Gourlay came agonisingly close to winning the second to take the match to a tie-break.
Djokovic exhibited more negative body language after Berdych held serve at 5-5, staring up at his coach in apparent disbelief, but the Serb quickly refocused, sending down some solid serves to take the set to a tie-break.
BBC: Novak Djokovic makes short work of Berdych in Melbourne
Cool under fire despite the two quick fouls, Hancock hit a 3-pointer from the left corner to break a 48-all tie with 50 seconds left as the Cardinals exacted a measure of revenge for a loss to the Orange earlier this season.
But Dodig hit back with his first break of the match and the set eventually went to a tie-break.
In Phoenix, he hit a grand slam to break a 2-2 tie and beat Italy.
Murray had beaten Nadal on three of their seven previous encounters but fell just short of matching the Majorcan at critical moments, notably in the second set, which went to a tie break.
Nadal stepped up a gear to break back at 5-3 before taking it on a tie-break and one break was enough in the third.
He had a chance to break Ferrero's serve in the eighth game but failed to capitalise as the set headed for a tie-break, in which he did enough to win.
But one break of serve saw a nervy-looking Murray concede the first set and, although he hit back in the second, three break points went begging in game one of the third set, which Roddick went on to take on a tie-break.
The second set also looked like going to a tie-break but at 6-5 Novak broke Henman to claim a semi-final berth.
She carried that momentum into the second set, winning the first four games before Pavlyuchenkova mounted a comeback to force a tie-break.
And when the opening set came down to a tie-break unusually it was Hewitt who faltered, missing with two forehands as Safin pressed.
However, Del Potro broke back when Federer was serving for the second set at 5-4 up, with the set eventually going to a tie-break.
It came down to a tie-break and Jankovic set about denying the Centre Court a second sensational match of the day as she moved 4-1 clear.
But Murray, who had beaten the world number 27 in both their previous meetings, hit seven aces in the second set, which went to a tie-break.
Parmar saved two set points at 4-5 down in the opening set to force a tie-break and then took advantage of a costly double-fault from his opponent to take it 7-3.
The veteran Finn triumphed 6-4 4-6 7-6 (7-4) against the 2009 U.S. Open champion as he was taken to a tie-break in the decider after the Argentine saved a match-point, before reaching his first Masters-level quarterfinal since 2006.
CNN: Nadal 'relaxed' as rivals struggle at Monte Carlo Masters
Having taken the first set to a tie-break, Soderling fought back from 4-2 down in the second set to level at 4-4 but Nadal -- who lost to Andy Murray in the final last year -- showed no signs of the inconsistency that plagued the latter half of his 2009 campaign as he clinched victory.
The mistake heralds a run of four lost points that prove enough to take the match into a tie-break.
Roddick, who been troubled by a shoulder injury this season, looked on his way to a straight-sets win but Mahut fought back to level the match in a tie-break.
The 27-year-old beat former champion and seven seed Jankovic despite letting slip a 5-2 lead in the first set, Martinez Sanchez eventually fighting back to win via a tie-break.
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