Substitute Gonzalo Higuain added a third after coming on as substitute to all but seal his side's place in the last four with 17 minutes remaining.
Jimmy Floyd Hasselbaink came off the bench to score Boro's third goal before fellow substitute Massimo Maccarone netted the winner at the death.
BBC: Massimo Maccarone's late goal sparked wild celebrations
Mirko Vucinic added a third six minutes later before substitute Alessandro Matri completed the rout with ten minutes remaining.
Lester's dismissal for a late lunge on Sammy Igoe ended their aspirations of a third goal, with Reading substitute Jamie Cureton coming close to netting a consolation at the death.
Substitute Pellissier struck the third 18 minutes from time as he turned and fired home from eight yards after being given too much room by Coates.
But it was Galatasaray who deservedly added a third with 12 minutes left, substitute Ilic escaping the attentions of the Liverpool defence - in which Argentine Gabriel Paletta was desperately uncertain - to slide home a simple finish.
Fernando Morientes fired home after 78 minutes, then substitute Shabani Nonda added a third four minutes later.
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Substitute Ben Burgess almost grabbed a third goal for the home side with a shot that whistled past the post.
In the second half Alex Song curled home to double the lead and substitute Nicklas Bendtner slotted in a third.
Fernando Torres curled in a precise pass from Xavi for Spain's third, and Juan Mata, a late substitute, capped the win with a fourth goal late on.
Substitute striker John Carew added a third from the penalty spot two minutes from time after Duke was booked for bringing down Ashley Young as Villa followed up the midweek win over Portsmouth that put Martin O'Neill's side in the semifinals of the League Cup.
United sealed the victory with a third goal two minutes before full-time, when substitute Dale Hilson sent the ball into the near post from the right and Gomis touched home his second and his side's third goal.
Substitute Walcott was then instrumental in England's third goal, racing to the byline and cutting the ball back for Welbeck to flick home a stunning backheel.
Gibson made an immediate impact by playing a major part in the Republic's third goal on 54 minutes with Christiansen unable to hold the substitute's long-range shot and Long reacting to fire home the rebound from 12 yards.
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The home side looked the more likely to add a third with Chris Maguire flashing a shot wide of the target and substitute Vujadinovic, who had replaced the injured Considine, heading over.
With United trailing 2-1 with half an hour to go, Macheda made his debut as a substitute and went on to hit the winning goal in the third minute of stoppage time.
Hull looked capable of soaking up everything the home side could throw at them until substitute Scharner knocked down a deep cross into the area in the third minute of stoppage time, and Gohouri turned the ball in.
Dortmund substitute Mario Goetze looked to have won it when he stabbed home for their third but Anderson salvaged a point for the home side after 73 minutes.
He made his international debut as a late substitute for England in the Euro 2008 qualifier against Andorra in Barcelona, scoring the third goal in a 3-0 victory.
The visitors eventually made their superiority count six minutes before the break when substitute Fa'asavalu took Sinfield's inside pass to get through a gap for a third try and the Leeds skipper kicked his second goal.
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