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It said that, although Nasa was taking steps to protect the shuttle from orbital debris such as spent rocket bodies, satellite fragments and paint chips - there was a real risk that a collision could cripple the shuttle or threaten the safety of the crew.
BBC: Was Columbia struck by space debris?
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We spent an entire day in the shuttle simulator, as the crew executed the duties closely mirroring the reality of a NASA mission.
FORBES: Space Shuttles and Motorcycles
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The past couple of years, most of that has been spent on fixing problems with the shuttle and getting ready to launch it again.
NPR: Is the Space Shuttle Worth the Effort?
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To prove the concept, an early version of AMS spent 10 days in space aboard space shuttle Discovery in 1998.
ENGADGET: AMS detects excess of positrons, could suggest existence of dark matter
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Rafael San Miguel began his career at NASA working on the Space Shuttle program, and has spent the past 23 years as a scientist for The Coca-Cola Company.
WHITEHOUSE: Rafael san miguel | The White House
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They spent a lot of this mission--they delivered the cargo that they had to the space station, but they spent a lot of the mission just making sure that the shuttle itself was safe to fly.
NPR: Shuttle Landing Delayed Due to Poor Weather
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Nyberg, 43, spent two weeks in space in 2008 as part of a U.S. space shuttle crew.
NPR: Soyuz Capsule Docks With Space Station
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But think about how much time you spent immobile: in a car or cab, in an airplane seat, on a bus or shuttle, in a meeting room or at a restaurant, watching TV in your hotel room.
BBC: Overweight frequent flyers