Takeda sells Actos, the world's top-selling diabetes pill, and Rozerem, a potential threat to sleep drugs like Lunesta and Ambien that so far hasn't taken off.

FORBES: Magazine Article

Also exciting: a stop-smoking pill, a long-delayed inhaled insulin, an osteoporosis medicine, a sleep drug and an antibiotic that can treat infections in a single dose.

FORBES: Pfizer's Tough Sell

For instance, AstraZeneca's (nyse: AZN - news - people ) Seroquel is often used for its sleep-promoting or calming effect. (see: " Antipsychotic Prescribed as Sleeping Pill") Eli Lilly 's (nyse: LLY - news - people ) Zyprexa has even been used in rare cases in patients with anorexia--one of the drug's potential side effects is weight gain.

FORBES: When Doctors Go Off-Label