High levels of TNF also are found in the skin of psoriasis patients.

FORBES: Chemical Chameleon

In a test of Enbrel on 19 psoriasis patients, on average half of the rash disappeared after three months, with few side effects.

FORBES: Chemical Chameleon

The immune-disease angle surfaced when doctors noticed that cancer patients who also had psoriasis found their skin improved when they took the immune suppressants methotrexate (for cancer) and cyclosporine (for organ transplants).

FORBES: Skin Deep

While a new treatment for psoriasis could be of value for these patients, this is probably not the type of breakthrough that GSK originally envisioned when they did this deal.

FORBES: Getting The Benefits Of Red Wine From A Pill? Not Likely.

Amevive is the first treatment for psoriasis, a skin disease that affects some 4 million patients in the U.S. It occurs because patients' immune systems run amok for unknown reasons, causing painful lesions and rashes.

FORBES: Magazine Article

Late-stage trials ended in May 2001, and the results were impressive:Of 1, 100 patients injected with Amevive, 40% achieved a 75% reduction in the severity of psoriasis.

FORBES: Skin Deep