One project is trying to carry the viral fragments which should trigger the immune response within another virus, called a parvovirus.
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Protection from HPV would be conferred by getting infected with the parvovirus.
"From our point of view since November, we've had five dogs that have had to be put down because of parvovirus and two that have died, " she said.
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At the local authority-run Cardiff Dogs Home, manager Maria Bailie said she had not seen any parvovirus cases until towards the end of last year but had now lost seven dogs to it.
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