Often the heart ends up being twice the size of a healthy heart.
The psychologist Dean Simonton argues that this fecundity is often at the heart of what distinguishes the truly gifted.
"Their music is often at the heart of the American story and speaks to folks across the country, " Mr Obama said.
As head of a national trade association of technology companies, I am often in the heart of Washington, where I can see, up close, the rot in our system.
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Abandonment, rejection, loss or ridicule often lay at the heart of many seemingly bizarre phobias.
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While on the surface procrastination often looks like laziness, at the heart of it lies fear.
The dance's punch line, almost an afterthought, has the most innocent and impecunious of the potential clients for the local Shady Ladies saved from being beaten to a pulp by the Procurers when one of the pimps appears to have the "heart of gold" often attributed to the sex workers in such fictions.
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Chest pain is the most common reason people visit the ER, but it is often not related to a problem with the heart.
Parlour often provided the graft in the heart of midfield at Highbury but nevertheless scored a spectacular goal against Chelsea in the 2002 FA Cup Final.
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Just last month, researchers led by Armin Arbab-Zadeh of Johns Hopkins University School of Medicine in Baltimore published a comprehensive review of the biology of heart attacks in the journal Circulation, which said that vulnerable plaques often rupture without causing a heart attack and that a "perfect storm" of other conditions is required before one occurs.
The diuretics most often used for heart failure, furosemide (Lasix) was introduced in 1966.
And that kind of vigorous back and forth -- that imperfect but well-founded process, messy as it often is -- is at the heart of our democracy.
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The Berlin party scene is not for the faint of heart, often wrapping up at 5 a.m.
Without this enzyme, the disease damages the heart and muscles, often fatally.
Small investors have often taken this to heart by rolling the dice on companies with a chance of becoming the next Google while shunning stodgy old industrials and soapmakers.
Thirsty years ago, economists of the left and the right often seemed to agree that the increase in the supply of capital were at the heart of development.
An unquestioned, and often unconscious, belief in Keynesianism is at the heart of clueless conservatism.
Social and moral dilemmas lie at the heart of their work, often emphasized with a heavy hand.
Defibrillator leads are often bound to the walls of veins and the heart by scar tissue, an obstacle that worsens with time.
The next step for such patients is often a heart transplant.
The irony of course is at the heart of the red-eye, a slang term used to describe the fatigued eyes often plaguing overnight flyers.
"Yet despite being the UK's single biggest killer, the first sign someone has heart disease is often severe chest pain or sudden death".
BBC: Dundee researchers develop tests for early heart disease
Drug companies often test new heart drugs on cardiac tissue, and the jellyfish which mimics a beating human heart could serve as an alternative model.
Post-mortem examination often reveals subtle, but nonetheless fatal, flaws in the heart muscle or kidneys of these animals the sorts of changes that are hard to predict and therefore almost impossible to prevent.
Often the hardest step in life is making a real commitment to follow your heart.
Heart studies often lump all of these factors together to increase the likelihood that they will be statistically significant.
Often the depth of their scars is not even close to the depth of heart pain that came with those scars.
The difficulty is that people do not often know their true level of heart disease risk - and may simply decide to treat themselves.
People often congregate around the large dining table in the kitchen area that acts as the heart of the office.
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