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It used to be thought that neural stem cells--which divide to produce nerve cells in an embryonic brain--shut down in adulthood.
ECONOMIST: Something new in mind
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Neural stem cells are, unsurprisingly, rather tricky to harvest from living patients.
ECONOMIST: Stem cells
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Surprisingly, the neural stem cells made their way far and wide in the developing embryos, from the nervous system to the liver, lung and intestine.
ECONOMIST: Stem cells
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The point of the exercise, though, was to see whether neural stem cells could be obtained reliably, with a view to using them as a treatment.
ECONOMIST: Stem cells
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To his delight, the extracted tissue thrived and grew, and many of the cells in the resulting culture did indeed contain proteins known to be characteristic of neural stem cells.
ECONOMIST: Stem cells
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He has managed to derive neural stem cells from 16 of these patients, out of a total of 22, and believes that success depends on which region of the brain is affected.
ECONOMIST: Stem cells
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Dr Frisen's team, together with NeuroNova, a Swedish biotech firm, is busy trying to identify some of these chemicals, and working out the genes and molecular pathways that are turned on in responsive neural stem cells.
ECONOMIST: Stem cells