Mr McCluskie is accused of killing Ms McCluskie sometime between 29 February and 6 March.
Tony McCluskie, 35, of Pelter Street, Hackney, is charged with the murder of his sister.
Tony McCluskie, 35, of Shoreditch, east London, denies murdering the 29-year-old and dumping her body parts.
Miss McCluskie played Kerry Skinner, the niece of Ethel Skinner, in the BBC soap in 2001.
Detectives interviewed McCluskie as a "significant witness" following the recovery of a torso from Regent's Canal.
Ms McLaren told the court she noticed bandages on McCluskie's hand shortly after his sister's disappearance.
Tony McCluskie, 35, from Shoreditch, east London, denies murdering former Eastenders' actress Gemma McCluskie but admits manslaughter.
Ms McCluskie, who played Kerry Skinner in the BBC soap in 2001, was officially identified by dental records.
Danny McCluskie, her other brother, also received a call with the same demands.
The defendant told police he had last seen Miss McCluskie when they argued over an overflowing sink, jurors heard.
The final straw came when McCluskie left taps running and a sink overflowed in March last year, the jury heard.
McCluskie told police that his sister was more heated towards him during the exchange and they would sometimes have "squabbles".
McCluskie, a window cleaner and skunk cannabis smoker, claimed to have lost control after a tirade of abuse from his sister.
Prof Black, from the University of Dundee, said Miss McCluskie's bones had 95 marks where they had been cut or hacked.
McCluskie, 35, of Pelter Street, Shoreditch, east London, denies murdering the 29-year-old and dumping her body parts in the Regent's Canal.
When McCluskie asked to speak to her, Dunne said she was in a locked room and had been stripped and sexually assaulted.
The prosecution allege McCluskie, of Pelter Street, killed his sister after a row about an overflowing sink in the flat they shared.
The expert in neuropsychiatry at the University of London assessed McCluskie while he was in custody at Belmarsh Prison following his arrest.
Prof Kopelman told the jury McCluskie said he suffered blackouts "infrequently" after drinking heavily and regularly smoking a strong form of cannabis.
An arm believed to belong to EastEnders actress Gemma McCluskie has been found in the east London canal where her torso was discovered.
Pathologist Dr Simon Poole told the court Miss McCluskie died from being hit over the head with an object such as a bat.
Claims by the brother of former Eastenders' actress Gemma McCluskie that he has no recollection of killing her are "feasible", a court heard.
Miss McCluskie's torso was found a week later when the case snapped open, and her limbs were found in plastic bags a week later.
Miss McCluskie's torso was found in a suitcase in the Regent's Canal in east London in March followed by her limbs in plastic bags.
McCluskie had shown symptoms of "mild moderate depression" on the Thursday, which progressed to "serious depression" during his time in custody, the court heard.
Nicole McLaren said she "felt sorry" for Tony McCluskie as they searched for his sister in the days following her disappearance, the Old Bailey heard.
Ms McLaren said she "felt sorry" for McCluskie when his brother Danny reacted angrily over his apparent confusion about when he last saw their sister.
The Old Bailey heard that on 2 March McCluskie lugged a heavy suitcase to a local cab firm and was seen taking it towards the canal.
McCluskie said there were "two sides" to his sister and told detectives that he felt "sick" when they asked how he felt about the discovery of a body.
Former EastEnders actress Gemma McCluskie was beaten over the head and killed before her body was hacked into six pieces with a meat cleaver, the Old Bailey has heard.
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