Like any major route, the canal played several roles, all of them indispensable to the empire.
The seven roads that meet at Seven Dials include the A2010, which is a major route through Brighton.
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The seven roads that meet at the junction include the A2010, which is a major route through Brighton.
Honduras is a major route for drugs smuggled from South to North America.
In Plymouth, engineers are surveying a major route into the city to find out if a sewer has collapsed or has a serious blockage.
Meanwhile, in the UK, some 300 lorry drivers demanding a fuel tax rebate blocked a major route into the capital during the morning rush hour in protest.
Britain's 16th Air Assault division, which has been protecting the Rumalia oil fields, have also extended their operation northwest toward Highway 6, a major route out of Basra.
Abu Kamal, home to a Red Crescent camp for Iraqi refugees, is across the border from the western Iraqi city of Qaim, which has been a major route for Sunni Arab fighters battling U.S. troops in Iraq.
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Their account said more than 34 government soldiers and police died on Sunday alone - an apparent setback for government forces a day after the army announced it had regained control of villages on a major route linking the central city of Hama to Aleppo, with security "restored" to the northern city's airport.
It is now Europe's sixth-largest economy, a major transit route for Europe's energy needs, and a serious regional power.
Take a scenic drive along the Turquoise Trail National Scenic Byway, "a major trade route since at least 2000 BC, " says BBC Travel.
Other fears are that the Asian economic recovery will prove less muscular than hoped (the port of Seattle is a major export route to Asia) and that the Department of Justice may carry out its veiled threats to break up Microsoft.
Dilmun, one of most important ancient civilisations of the region and said to date to the third millennium BC, was a hub on a major trading route between Mesopotamia - the world's oldest civilisation - and the Indus Valley in South Asia.
The valley is "a major through-route" for transporting fighters and munitions from east to west and north to south, said Pelletier, who's at at Camp Leatherneck in Helmand.
Europe already has a major mission en route to Jupiter's orbit - the Rosetta mission, which will chase down a comet and put a lander on its surface.
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"International navies are the only ones capable of effective response against piracy in the region and can help to secure the safety and security of this major maritime trade route, " Mukundan said.
In October 2010 it was confirmed the Department for Transport Major Scheme Bid funding route was no longer available for new entrants.
The government is considering an alternative route for a major trade highway that would run to the south of the park.
The route was a major feature of the new timetable launched by the company when they took over the service in January.
The route is a major highway in Quebec and its extension was included in Plan Nord, an initiative announced last month by mining firms and the provincial government to develop gold and other mining projects in northern Quebec.
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"You can look at isolating particular areas and trying to secure these -- however, you are looking at a 26-mile-plus route, which often will spread across a major capital, and in terms of protecting it right along the route, it will be very, very difficult, " he said.
But where the implosion of the NASL in the 80s was caused by a rapid expansion of teams that had only served to exaggerate the deadly concept of the weakest link, Major League Soccer decided that the route to success was more likely to be found through contraction.
Ron Roenicke has taken a long and circuitous route to managing in the major leagues.
The absence of the major New York airports from Southwest's route map was a glaring flaw in the eyes of many business travellers.
Ian Jordan, HS2 Ltd director for Leeds, Manchester and Heathrow, said the line would bring major economic benefits and public consultations on the route would start later this year.
But, in its mid 19th-century heyday, it was a terminus of the caravan route from Lake Tanganyika, a major export point for slaves and ivory, and one of the largest ports between the city of Bagamoyo and Mombasa, Kenya.
The road was reopened Sunday morning, but a major exit -- the Fort Washington exit onto Route 309 -- remained closed.
August saw small decreases in Isle of Man passengers across many routes, with the major impact coming from the withdrawal of the Southampton route, which had generated more than 1, 800 passengers in August 2011.
For riders on the Carretera Austral, this could mean years of major roadworks and heavy dam-building machinery on the route.
Eventually the US government stepped in, sending the army under Major Richardson to construct, for real, the fanciful route into the hinterland the steamship companies had promised.
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