By contrast, vancomycin is given twice a day, and Cubicin, a medicine marketed by Lexington, Mass.
"The loudest critics now are the investors, " says retail consultant Doug Fleener of Dynamic Experiences Group in Lexington, Mass.
Of 32, 195 small-business owners who responded to a survey conducted last April by VistaPrint, a custom-printing house in Lexington, Mass.
Then there are the truly unorthodox investors, like Rajeev Kotyan, 43, a partner in the financial firm NUA Advisors, in Lexington, Mass.
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Cubist Pharmaceuticals in Lexington, Mass. is waiting for approval on Cidecin, an injection for treating hospital-acquired skin infections, which was discovered and then mothballed by Eli Lilly.
"They have the sheer power of simple mutations, " says Francis Tally, chief scientist at Cubist Pharmaceuticals (nasdaq: CBST - news - people ) in Lexington, Mass.
The Lexington, Mass. company, run by husband and wife team Andrew Prihodko and Sharon Peyer, operates a Netflix-like app for iOS and Android that gives users access to a whole slew of TV shows and movies.
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After the first oil shock in 1973 it didn't take long for Americans to return to their gas-guzzling ways, with a preference for large cars and big V8 engines, says automotive analyst John Wolkonowicz, of consultant Global Insight in Lexington, Mass.
Being able to prove a business concept in a hurry, even if the product isn't perfect, is especially attractive to investors, says Peter Bell, general partner with Highland Capital Partners, a venture firm in Lexington, Mass. that staked Digg, Mapquest and Ask Jeeves.
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