Meanwhile reigning two-time champion Jelena Jankovic barely had to break sweat as she coasted into the last eight when KaterynaBondarenko retired with an illness.
Fourth seed Victoria Azarenka of Belarus also profited from an injury as U.S. Open quarterfinalist KaterynaBondarenko of the Ukraine conceded while 4-1 down in the first set.
Third seed Venus will next face Ukrainian KaterynaBondarenko after a 6-3 6-2 victory over the world number 97 who was making her debut at the All England Club.
Pennetta helped defending champions Italy to end the day level 1-1 with Ukraine, beating KaterynaBondarenko 7-5 6-3 after Francesca Schiavone lost the opening match 6-1 6-4 to the elder Bondarenko sister Alona in Kharkiv.
Monday proved an excellent day for the seeded women as Elena Dementieva (5), Sam Stosur (7), Agnieszka Radwanska (8), Li Na (11), Lucie Safarova (24), Alisa Kleybanova (28) and KaterynaBondarenko (32) all went through without dropping a set.